Geroscience posits that cardiovascular disease (CVD) and other chronic diseases result
from progressive erosion of the effectiveness of homeostatic mechanisms that oppose age …

Geriatricians and others must embrace the emerging field of geroscience. Until recently
geroscience research was pursued in laboratory animals, but now this field requires …

Age is the greatest risk factor for nearly every major cause of mortality in developed nations.
Despite this, most biomedical research focuses on individual disease processes without …

For many years, it was believed that the aging process was inevitable and that age‐related
diseases could not be prevented or reversed. The geroscience hypothesis, however, posits …

Advances in geroscience are allowing scientists and clinicians, for the first time, to consider
interventions aimed at directly targeting the hallmarks of aging. Unlike disease-specific …

Aging remains the most pervasive risk factor for a wide range of chronic diseases that afflict
modern societies. In the United States alone, incidence of age-related diseases (eg …

Common chronic diseases represent the greatest driver of rising healthcare costs, as well as
declining function, independence, and quality of life. Geroscience‐guided approaches seek …

For decades, researchers in the biology of aging have focused on defining mechanisms that
modulate aging by primarily studying a single metric, sometimes described as the “gold …

Mammalian aging can be delayed with genetic, dietary, and pharmacologic approaches.
Given that the elderly population is dramatically increasing and that aging is the greatest risk …

Research on the biology of aging has accelerated rapidly in the last two decades. It is now at
the point where translation of the findings into useful approaches to improve the health of the …