Mitochondria are important for providing cellular energy ATP through the oxidative
phosphorylation pathway. They are also critical in regulating many cellular functions …

[Frontiers in Bioscience 12, 1107-1123, January 1, 2007] 1107 Mitochondrial dysfunction, free
radical generation and cellular st Page 1 [Frontiers in Bioscience 12, 1107-1123, January 1 …

Mitochondria are involved in ATP supply to cells through oxidative phosphorylation
(OXPHOS), synthesis of key molecules and response to oxidative stress, as well as in …

Mitochondria are the double membrane organelles providing most of the energy for cells. In
addition, mitochondria also play essential roles in various cellular biological processes such …

Dysfunctional mitochondria are thought to play a cardinal role in the pathogenesis of various
neurological disorders, such as multiple sclerosis, Alzheimer's disease, Parkinson's disease …

Mitochondria play a critical role in several metabolic processes and apoptotic pathways,
regulating life cycle from the cradle to the grave. Despite the evidence of morphological …

Oxidative stress and mitochondrial damage have been implicated in the pathogenesis of
several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease …

Reactive species play an important role in physiological functions. Overproduction of
reactive species, notably reactive oxygen (ROS) and nitrogen (RNS) species along with the …

Mitochondrial function is vital for normal cellular processes. Mitochondrial damage and
oxidative stress have been greatly implicated in the progression of aging, along with the …

Misfolded proteins in the central nervous system can induce oxidative damage, which can
contribute to neurodegenerative diseases in the mitochondria. Neurodegenerative patients …