MRI‐Guided Tumor Therapy Based on Synergy of Ferroptosis, Immunosuppression Reversal and Disulfidptosis
S Guo, Z Li, R Zhou, J Feng, L Huang, B Ren, J Zhu… - Small, 2024 - Wiley Online Library
Triple negative breast cancer (TNBC) cells have a high demand for oxygen and glucose to
fuel their growth and spread, shaping the tumor microenvironment (TME) that can lead to a …
fuel their growth and spread, shaping the tumor microenvironment (TME) that can lead to a …
A MOF-based potent ferroptosis inducer for enhanced radiotherapy of triple negative breast cancer
L Zeng, S Ding, Y Cao, C Li, B Zhao, Z Ma, J Zhou… - ACS …, 2023 - ACS Publications
Radiotherapy (RT) is one of the important clinical treatments for local control of triple-
negative breast cancer (TNBC), but radioresistance still exists. Ferroptosis has been …
negative breast cancer (TNBC), but radioresistance still exists. Ferroptosis has been …
[HTML][HTML] MR imaging guided iron-based nanoenzyme for synergistic Ferroptosis− Starvation therapy in triple negative breast cancer
D Wang, W Fang, C Huang, Z Chen, T Nie… - Smart Materials in …, 2022 - Elsevier
Triple negative breast cancer (TNBC), as the most aggressive BC, accounts for the leading
cause of worldwide women death. Owing to the deficiency of related hormone receptors, the …
cause of worldwide women death. Owing to the deficiency of related hormone receptors, the …
A multi-mode Rhein-based nano-platform synergizing ferrotherapy/chemotherapy-induced immunotherapy for enhanced tumor therapy
X Zhu, L Xie, J Tian, Y Jiang, E Song, Y Song - Acta Biomaterialia, 2024 - Elsevier
Ferroptosis has emerged as a promising strategy for treating triple-negative breast cancer
(TNBC) due to bypassing apoptosis and triggering immunogenic cell death (ICD) of tumor …
(TNBC) due to bypassing apoptosis and triggering immunogenic cell death (ICD) of tumor …
Enhanced ferroptosis therapy with a “nano-destructor” by disrupting intracellular redox and iron homeostasis
T Song, G Yang, H Zhang, M Li, W Zhou, C Zheng… - Nano Today, 2023 - Elsevier
Ferroptosis is an iron-dependent form of cell death that is also a promising tumor therapeutic
modality, however, maintaining redox and iron homeostasis in tumor cells limits the …
modality, however, maintaining redox and iron homeostasis in tumor cells limits the …
Functionalized tumor‐targeting nanosheets exhibiting Fe (II) overloading and GSH consumption for ferroptosis activation in liver tumor
Liver tumor is difficult to cure for its high degree of malignancy and rapid progression
characteristics. Ferroptosis as a new model of inducing cell death is expected to break the …
characteristics. Ferroptosis as a new model of inducing cell death is expected to break the …
Manganese‐Based Redox Homeostasis Disruptor for Inducing Intense Ferroptosis/Apoptosis Through xCT Inhibition And Oxidative Stress Injury
Q Dong, J Wang, J Liu, L Zhang, Z Xu… - Advanced …, 2023 - Wiley Online Library
Intracellular redox homeostasis plays an important role in promoting tumor progression,
development and even treatment resistance. To this end, redox balance impairment may …
development and even treatment resistance. To this end, redox balance impairment may …
Self-cascade nanohybrids boost cell ferroptosis stress for tumor radiosensitization therapy
Q Wu, M Hou, P Zhang, Y Jiang, M Liu, L Xiong… - Applied Materials …, 2022 - Elsevier
Although ferroptosis plays a potential role in sensitizing tumor radiotherapy, its
radiosensitization efficacy is still limited by insufficient endogenous H 2 O 2 and excess …
radiosensitization efficacy is still limited by insufficient endogenous H 2 O 2 and excess …
Precision therapy through breaking the intracellular redox balance with an MOF-based hydrogel intelligent nanobot for enhancing ferroptosis and activating …
D Zhang, Y Meng, Y Song, P Cui, Z Hu, X Zheng - Nanoscale, 2022 - pubs.rsc.org
With the advancement and development of nanomedicine, tumor precision therapy provides
technical support for effective accumulation and targeted drug delivery, and reduces toxic …
technical support for effective accumulation and targeted drug delivery, and reduces toxic …
A tumor microenvironment responsive nanoplatform with oxidative stress amplification for effective MRI-based visual tumor ferroptosis
S Luo, D Ma, R Wei, W Yao, X Pang, Y Wang, X Xu… - Acta Biomaterialia, 2022 - Elsevier
As a promising new form of non-apoptotic regulated cell death, ferroptosis has potential as
an effective supplement to apoptosis-based cancer treatments. However, high intracellular …
an effective supplement to apoptosis-based cancer treatments. However, high intracellular …