Cancer metabolism is an extensively studied field since the discovery of the Warburg effect
about 100 years ago and continues to be increasingly intriguing and enigmatic so far. It has …

Warburg suggested that the alterations in metabolism that he observed in cancer cells were
due to the malfunction of mitochondria. In the past decade, we have revisited this idea and …

Cancer is a disease characterized by uncontrolled growth. Metabolic demands to sustain
rapid proliferation must be compelling since aerobic glycolysis is the first as well as the most …

Tumors remodel their metabolism to support anabolic processes needed for replication, as
well as to survive nutrient scarcity and oxidative stress imposed by their changing …

Since Otto Warburg first proposed that cancer cells have defective mitochondrial metabolism
with enhanced aerobic glycolysis almost 100 years ago, uncovering the unique metabolic …

Recently, the inevitable metabolic reprogramming experienced by cancer cells as a result of
the onset of cellular proliferation has been added to the list of hallmarks of the cancer cell …

The mitochondrion is an important organelle and provides energy for a plethora of
intracellular reactions. Metabolic dysregulation has dire consequences for the cell, and …

Oxidative phosphorylation (OxPhos) is functional and sustains tumor proliferation in several
cancer cell types. To establish whether mitochondrial β-oxidation of free fatty acids (FFAs) …

Metabolic alterations have been observed in many cancer types. The deregulated
metabolism has thus become an emerging hallmark of the disease, where the metabolism is …

Anomalous increase in glycolytic activity defines one of the key metabolic alterations in
cancer cells. A realization of this feature has led to critical advancements in cancer detection …