MiR-146a-5p enrichment in small-extracellular vesicles of relapsed pediatric ALCL patients promotes macrophages infiltration and differentiation
A Garbin, G Contarini, CC Damanti, A Tosato… - Biochemical …, 2023 - Elsevier
Anaplastic large cell lymphoma (ALCL) is a CD30-positive lymphoma accounting for 20% of
all pediatric T-cell lymphomas. Current first line treatment can cure most of ALCL patients but …
all pediatric T-cell lymphomas. Current first line treatment can cure most of ALCL patients but …
[HTML][HTML] Plasma small‐extracellular vesicles enriched in miR‐122‐5p promote disease aggressiveness in pediatric anaplastic large‐cell lymphoma
Dear Editor, Anaplastic lymphoma kinase-positive (ALK+) anaplastic large cell lymphoma
(ALCL) is an aggressive peripheral T-cell lymphoma representing 10%-15% of pediatric …
(ALCL) is an aggressive peripheral T-cell lymphoma representing 10%-15% of pediatric …
[HTML][HTML] Low miR-214-5p expression correlates with aggressive subtypes of pediatric ALCL with non-common histology
The unsatisfactory cure rate of relapsing ALK-positive Anaplastic Large-Cell Lymphoma
(ALCL) of childhood calls for the identification of new prognostic markers. Here, the small …
(ALCL) of childhood calls for the identification of new prognostic markers. Here, the small …
[HTML][HTML] Increased tenascin C, osteopontin and HSP90 levels in plasmatic small extracellular vesicles of pediatric ALK-positive anaplastic large cell lymphoma: new …
F Lovisa, A Garbin, S Crotti, P Di Battista, I Gallingani… - Diagnostics, 2021 - mdpi.com
Over the past 15 years, several biological and pathological characteristics proved their
significance in pediatric anaplastic lymphoma kinase (ALK)-positive anaplastic large-cell …
significance in pediatric anaplastic lymphoma kinase (ALK)-positive anaplastic large-cell …
[HTML][HTML] MiR-128-3p as blood based liquid biopsy biomarker in childhood acute lymphoblastic leukemia
A Rzepiel, A Horváth, N Kutszegi, A Gézsi… - Molecular and Cellular …, 2023 - Elsevier
Background Minimal residual disease (MRD) is one of the most valuable independent
prognostic factors in acute lymphoblastic leukemia (ALL). Bone marrow (BM) aspiration …
prognostic factors in acute lymphoblastic leukemia (ALL). Bone marrow (BM) aspiration …
The role of exosomal miR-181b in the crosstalk between NSCLC cells and tumor-associated macrophages
J Ma, S Chen, Y Liu, H Han, M Gong, Y Song - Genes & Genomics, 2022 - Springer
Background It has been reported that tumor-associated macrophages (TAMs) participate in
modulating the progression of cancer in the tumor microenvironment. However, the crosstalk …
modulating the progression of cancer in the tumor microenvironment. However, the crosstalk …
[HTML][HTML] miR-939 acts as tumor suppressor by modulating JUNB transcriptional activity in pediatric anaplastic large cell lymphoma
A Garbin, F Lovisa, AB Holmes, CC Damanti… - …, 2021 - ncbi.nlm.nih.gov
Anaplastic large cell lymphoma (ALCL) is a distinct subtype of aggressive non-Hodgkin
lymphoma, mainly affecting children and young adults. The vast majority of the pediatric …
lymphoma, mainly affecting children and young adults. The vast majority of the pediatric …
Identification of putative pathogenic microRNA and its downstream targets in anaplastic lymphoma kinase–negative anaplastic large cell lymphoma
Anaplastic large cell lymphomas (ALCL) are tumors of T/null-cell lineage characterized by
uniform CD30 expression. The 2008 World Health Organization classification subdivided …
uniform CD30 expression. The 2008 World Health Organization classification subdivided …
[HTML][HTML] MicroRNA-181a as novel liquid biopsy marker of central nervous system involvement in pediatric acute lymphoblastic leukemia
Background Refractory central nervous system (CNS) involvement is among the major
causes of therapy failure in childhood acute leukemia. Applying contemporary diagnostic …
causes of therapy failure in childhood acute leukemia. Applying contemporary diagnostic …
[HTML][HTML] Tumor cell-derived exosomal microRNA-146a promotes non-small cell lung cancer cell invasion and proliferation by inhibiting M1 macrophage polarization
Z Yan, JX Wen, XS Cao, W Zhao, YL Han… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Tumor-associated macrophages (TAMs) affects the outcomes of non-small cell
lung cancer (NSCLC). NSCLC cells released exosomes to suppress the antitumor activity of …
lung cancer (NSCLC). NSCLC cells released exosomes to suppress the antitumor activity of …