Role of peripheral 5-HT4, 5-HT6, and 5-HT7 receptors in development and maintenance of secondary mechanical allodynia and hyperalgesia
B Godínez-Chaparro, P Barragán-Iglesias… - PAIN®, 2011 - Elsevier
The role of 5-hydroxytryptamine (5-HT) 4, 5-HT6, and 5-HT7 receptors in formalin-induced
secondary allodynia and hyperalgesia in rats was assessed. Formalin produced acute …
secondary allodynia and hyperalgesia in rats was assessed. Formalin produced acute …
Evidence for the participation of peripheral 5-HT2A, 5-HT2B, and 5-HT2C receptors in formalin-induced secondary mechanical allodynia and hyperalgesia
C Cervantes-Durán, JB Pineda-Farias… - Neuroscience, 2013 - Elsevier
The role of 5-HT2A/2B/2C receptors in formalin-induced secondary allodynia and
hyperalgesia in rats was assessed. Formalin produced acute nociceptive behaviors …
hyperalgesia in rats was assessed. Formalin produced acute nociceptive behaviors …
Role of peripheral and spinal 5-HT3 receptors in development and maintenance of formalin-induced long-term secondary allodynia and hyperalgesia
M Bravo-Hernández, C Cervantes-Durán… - Pharmacology …, 2012 - Elsevier
The role of peripheral and spinal 5-HT3 receptors in formalin-induced secondary allodynia
and hyperalgesia in rats was assessed. Formalin produced acute nociceptive behaviors …
and hyperalgesia in rats was assessed. Formalin produced acute nociceptive behaviors …
Secondary mechanical allodynia and hyperalgesia depend on descending facilitation mediated by spinal 5-HT4, 5-HT6 and 5-HT7 receptors
B Godínez-Chaparro, FJ López-Santillán, P Orduña… - Neuroscience, 2012 - Elsevier
In the present study we determined the role of spinal 5-hydroxytriptamine (5-HT) and 5-
HT4/6/7 receptors in the long-term secondary mechanical allodynia and hyperalgesia …
HT4/6/7 receptors in the long-term secondary mechanical allodynia and hyperalgesia …
Role of spinal 5-HT2 receptors subtypes in formalin-induced long-lasting hypersensitivity
C Cervantes-Durán, GC Vidal-Cantú… - Pharmacological …, 2016 - Springer
Background The purpose of this study was to determine the role of spinal 5-HT 2A, 5-HT 2B
and 5-HT 2C receptors in the development and maintenance of formalin-induced long …
and 5-HT 2C receptors in the development and maintenance of formalin-induced long …
The nociceptive mechanism of 5-hydroxytryptamine released into the peripheral tissue in acute inflammatory pain in rats
K Nakajima, H Obata, N Ito, F Goto, S Saito - European Journal of Pain, 2009 - Elsevier
The present study examined the contribution of 5-hydroxytryptamine (5-HT) to acute
peripheral inflammatory pain in rats. We used formalin test in this study. After formalin …
peripheral inflammatory pain in rats. We used formalin test in this study. After formalin …
[HTML][HTML] Role of peripheral 5-HT1D, 5-HT3 and 5-HT7 receptors in the mechanical allodynia induced by serotonin in mice
EB Nascimento Jr, TRL Romero, MMGB Dutra… - Biomedicine & …, 2021 - Elsevier
Abstract Serotonin (5-HT) acts as a neurotransmitter in the central nervous system (CNS)
and as a mediator released by enterochromaffin cells to regulate intestinal motility. However …
and as a mediator released by enterochromaffin cells to regulate intestinal motility. However …
5-HT acts on nociceptive primary afferents through an indirect mechanism to induce hyperalgesia in the subcutaneous tissue
MCG Oliveira, A Pelegrini-da-Silva, CA Parada… - Neuroscience, 2007 - Elsevier
We have recently demonstrated that sc-injected 5-hydroxytryptamine (5-HT) induces
nociception by an indirect action on the primary afferent nociceptor in addition to its …
nociception by an indirect action on the primary afferent nociceptor in addition to its …
Profound, Non-Opioid Analgesia Produced by the High-Efficacy 5-HT1A Agonist F 13640 in the Formalin Model of Tonic Nociceptive Pain
L Bardin, JP Tarayre, N Malfetes, W Koek, FC Colpaert - Pharmacology, 2003 - karger.com
Previously, we have reported that in rat models of chronic pain, in particular, the very-high-
efficacy 5-HT1A agonist F 13640 induces unprecedented pain relief by novel …
efficacy 5-HT1A agonist F 13640 induces unprecedented pain relief by novel …
Contribution of the peripheral 5-HT2A receptor to mechanical hyperalgesia in a rat model of neuropathic pain
A Nitanda, N Yasunami, K Tokumo, H Fujii… - Neurochemistry …, 2005 - Elsevier
We investigated the effect of 5-HT receptor antagonists on mechanical hyperalgesia
observed in a neuropathic pain rat model prepared by chronic constriction injury of the …
observed in a neuropathic pain rat model prepared by chronic constriction injury of the …