Options for field diagnosis of human African trypanosomiasis

F Chappuis, L Loutan, P Simarro, V Lejon… - Clinical microbiology …, 2005 - Am Soc Microbiol
Human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense or T. b.
rhodesiense remains highly prevalent in several rural areas of sub-Saharan Africa and is …

Human African trypanosomiasis diagnosis in first-line health services of endemic countries, a systematic review

P Mitashi, E Hasker, V Lejon, V Kande… - PLoS neglected …, 2012 - journals.plos.org
While the incidence of Human African Trypanosomiasis (HAT) is decreasing, the control
approach is shifting from active population screening by mobile teams to passive case …

Sensitivity and Specificity of a Prototype Rapid Diagnostic Test for the Detection of Trypanosoma brucei gambiense Infection: A Multi-centric Prospective Study

S Bisser, C Lumbala, E Nguertoum… - PLoS neglected …, 2016 - journals.plos.org
Background A major challenge in the control of human African trypanosomiasis (HAT) is lack
of reliable diagnostic tests that are rapid and easy to use in remote areas where the disease …

Prospective evaluation of a rapid diagnostic test for Trypanosoma brucei gambiense infection developed using recombinant antigens

C Lumbala, S Bieler, S Kayembe… - PLoS neglected …, 2018 - journals.plos.org
Background Diagnosis and treatment are central elements of strategies to control
Trypanosoma brucei gambiense human African trypanosomiasis (HAT). Serological …

Recent progress in diagnosis and treatment of Human African Trypanosomiasis has made the elimination of this disease a realistic target by 2030

A Álvarez-Rodríguez, BK Jin, M Radwanska… - Frontiers in …, 2022 - frontiersin.org
Human African Trypanosomiasis (HAT) is caused by unicellular flagellated protozoan
parasites of the genus Trypanosoma brucei. The subspecies T. b. gambiense is mainly …

Follow‐up of Card Agglutination Trypanosomiasis Test (CATT) positive but apparently aparasitaemic individuals in Côte d'Ivoire: evidence for a complex and …

A Garcia, V Jamonneau, E Magnus… - Tropical Medicine & …, 2000 - Wiley Online Library
The aetiological diagnosis of human African trypanosomiasis (HAT) is based on the
detection of the parasite, but currently available parasitological tests have low sensitivity and …

Atypical human infections by animal trypanosomes

P Truc, P Büscher, G Cuny, MI Gonzatti… - PLoS Neglected …, 2013 - journals.plos.org
The two classical forms of human trypanosomoses are sleeping sickness due to
Trypanosoma brucei gambiense or T. brucei rhodesiense, and Chagas disease due to T …

Human African trypanosomiasis presenting at least 29 years after infection—what can this teach us about the pathogenesis and control of this neglected tropical …

D Sudarshi, S Lawrence, WO Pickrell… - PLoS neglected …, 2014 - journals.plos.org
The World Health Organization (WHO) has recently announced its plan to eliminate Human
African trypanosomiasis (HAT). The plan's main focus is on the Trypanosoma brucei …

A novel and accurate diagnostic test for human African trypanosomiasis

MC Papadopoulos, PM Abel, D Agranoff, A Stich… - The Lancet, 2004 - thelancet.com
Summary Introduction Human African trypanosomiasis (sleeping sickness) affects up to half
a million people every year in sub-Saharan Africa. Because current diagnostic tests for the …

Nucleic Acid Sequence-Based Amplification with Oligochromatography for Detection of Trypanosoma brucei in Clinical Samples

CM Mugasa, T Laurent, GJ Schoone… - Journal of Clinical …, 2009 - Am Soc Microbiol
Molecular tools, such as real-time nucleic acid sequence-based amplification (NASBA) and
PCR, have been developed to detect Trypanosoma brucei parasites in blood for the …