Cytokinesis in fission yeast involves actomyosin ring constriction concurrent to septum
synthesis followed by septum digestion resulting in cell separation. A recent report indicates …

Fission yeast cytokinesis is driven by simultaneous septum synthesis, membrane furrowing
and actomyosin ring constriction. The septum consists of a primary septum flanked by …

The Rho-family GTPase Cdc42 regulates cell polarity and localizes to the cell division site.
Cdc42 is activated by guanine nucleotide exchange factors (GEFs). We report that Cdc42 …

In fission yeast, cytokinesis requires a contractile actomyosin ring (CR) coupled to
membrane and septum ingression. Septation proceeds in two phases. In anaphase B, the …

Cytokinesis in many organisms requires a plasma membrane anchored actomyosin ring,
whose contraction facilitates cell division. In yeast and fungi, actomyosin ring constriction is …

Cdc42, a conserved regulator of cell polarity, is activated by two GEFs, Gef1 and Scd1, in
fission yeast. Why the cell needs two GEFs is unclear, given that they are partially redundant …

Abstract Cdc42, a Rho-family GTPase, is a master regulator of cell polarity. Recently, it has
been shown that Cdc42 also facilitates proper cytokinesis in the fission yeast …

The septation initiation network (SIN) serves to coordinate cytokinesis with mitotic exit in the
fission yeast Schizosaccharomyces pombe. SIN components Spg1 and Cdc7 together play …

The septation initiation network (SIN), comprising a GTPase and a cascade of three protein
kinases, regulates cell division in fission yeast Schizosaccharomyces pombe, but questions …

Rho GTPases, activated by Rho guanine nucleotide exchange factors (GEFs), are
conserved molecular switches for signal transductions that regulate diverse cellular …