Tumor angiogenesis is a hallmark of advanced cancers and promotes invasion and
metastasis. Over 90% of head and neck squamous cell carcinomas (HNSCC) express …

Tumor angiogenesis is a hallmark of advanced cancers and an attractive treatment target in
multiple solid tumors. In the past 5 years anti-angiogenic therapies have seen a rapid ascent …

Angiogenesis is a crucial step in tumor growth and metastasis. Head and neck squamous
cell carcinomas (HNSCC) highly express angiogenesis factors, such as vascular endothelial …

Angiogenesis is a necessary process for tumor growth, progression and diffusion. In the last
years many efforts have been made to understand the mechanisms necessary to the …

Angiogenesis is a necessary process for tumor progression and is driven through molecular
interactions between cancer cells and neighboring vascular endothelial cells. The primary …

Angiogenesis is an integral aspect of the growth and proliferation of solid tumors, including
head and neck squamous cell carcinoma (HNSCC), and has potential implications in …

Oxygen/drug supply to cancer cells is an important factor defining response to radiotherapy
and chemotherapy. Although tumor angiogenesis is considered an important prognostic …

Background and purpose Intra-tumoural neoangiogenesis is an essential process for tumour
progression. Although intensification of angiogenic pathways during cytotoxic therapy has …

Despite refinements to diagnostic and therapeutic approaches over the last two decades,
the outcome of patients with head and neck squamous cell carcinoma (HNSCC) has not …

Recent preclinical studies have suggested that radiotherapy in combination with
antiangiogenic/vasculature targeting agents enhances the therapeutic ratio of ionizing …