Bioactive composite hydrogels as 3D mesenchymal stem cell encapsulation environment for bone tissue engineering: in vitro and in vivo studies

MT Vurat, M Parmaksiz, AE Elçin… - Journal of Biomedical …, 2023 - Wiley Online Library
Although decellularized bone matrix (DBM) has often been used in scaffold form for
osteogenic applications, its use as a stem cell encapsulation matrix adaptable to surgical …

Decellularized bone matrix/oleoyl chitosan derived supramolecular injectable hydrogel promotes efficient bone integration

S Datta, AP Rameshbabu, K Bankoti, M Roy… - Materials Science and …, 2021 - Elsevier
Hydrogels derived from decellularized extracellular matrix (ECM) have been widely used as
a bioactive matrix for facilitating functional bone tissue regeneration. However, its poor …

Biomimetic methacrylated gelatin hydrogel loaded with bone marrow mesenchymal stem cells for bone tissue regeneration

J Li, W Wang, M Li, P Song, H Lei, X Gui… - … in bioengineering and …, 2021 - frontiersin.org
Large-segment bone defect caused by trauma or tumor is one of the most challenging
problems in orthopedic clinics. Biomimetic materials for bone tissue engineering have …

[HTML][HTML] 3D printed gelatin/decellularized bone composite scaffolds for bone tissue engineering: Fabrication, characterization and cytocompatibility study

A Kara, T Distler, C Polley, D Schneidereit, H Seitz… - Materials Today Bio, 2022 - Elsevier
Abstract Three-dimensional (3D) printing technology enables the design of personalized
scaffolds with tunable pore size and composition. Combining decellularization and 3D …

Synergistic interplay between human MSCs and HUVECs in 3D spheroids laden in collagen/fibrin hydrogels for bone tissue engineering

DN Heo, M Hospodiuk, IT Ozbolat - Acta biomaterialia, 2019 - Elsevier
Stem cell encapsulation in hydrogels has been widely employed in tissue engineering,
regenerative medicine, organ-on-a-chip devices and gene delivery; however, fabrication of …

3D-HA scaffold functionalized by extracellular matrix of stem cells promotes bone repair

H Chi, G Chen, Y He, G Chen, H Tu, X Liu… - International Journal …, 2020 - Taylor & Francis
Background and Purpose The extracellular matrix (ECM) derived from bone marrow
mesenchymal stem cells (BMSCs) has been used in regenerative medicine because of its …

Injectable hydrogels based on MPEG–PCL–RGD and BMSCs for bone tissue engineering

HJ Kim, SJ You, DH Yang, J Eun, HK Park… - Biomaterials …, 2020 - pubs.rsc.org
The aim of this study was to investigate the osteogenic potential of bone marrow-derived
mesenchymal stem cells (BMSCs) seeded on novel thermosensitive in situ forming hydrogel …

[HTML][HTML] Biomimetic composite gelatin methacryloyl hydrogels for improving survival and osteogenesis of human adipose-derived stem cells in 3D microenvironment

E Kim, J Lee, SJ Kim, EM Kim, H Byun, SJ Huh, E Lee… - Materials Today Bio, 2024 - Elsevier
Gelatin methacryloyl (GelMA) hydrogels are used for stem cell encapsulation in bone tissue
engineering due to their fast and stable photo-crosslinking. However, cell viability and ability …

Injectable polypeptide hydrogels with tunable microenvironment for 3D spreading and chondrogenic differentiation of bone-marrow-derived mesenchymal stem cells

K Ren, H Cui, Q Xu, C He, G Li, X Chen - Biomacromolecules, 2016 - ACS Publications
Bone-marrow-derived mesenchymal stem cells (BMSCs) possess vast potential for tissue
engineering and regenerative medicine. In this study, an injectable hydrogel comprising …

Bioprinting organotypic hydrogels with improved mesenchymal stem cell remodeling and mineralization properties for bone tissue engineering

DF Duarte Campos, A Blaeser… - Advanced …, 2016 - Wiley Online Library
3D‐manufactured hydrogels with precise contours and biological adhesion motifs are
interesting candidates in the regenerative medicine field for the culture and differentiation of …