Pharmacokinetic profile of a 2-month dose regimen of aripiprazole lauroxil: a phase I study and a population pharmacokinetic model

ML Hard, RJ Mills, BM Sadler, AY Wehr, PJ Weiden… - CNS drugs, 2017 - Springer
Background Aripiprazole lauroxil (AL) is a long-acting injectable medication approved for
the treatment of schizophrenia. Current AL regimens are 441 mg, 662 mg, and 882 mg …

Pharmacokinetics, safety, and tolerability of a 2-month dose interval regimen of the long-acting injectable antipsychotic aripiprazole lauroxil: results from a 44-week …

PJ Weiden, Y Du, L von Moltke, A Wehr, M Hard… - CNS drugs, 2020 - Springer
Background Aripiprazole lauroxil (AL) is a long-acting injectable antipsychotic approved for
treatment of schizophrenia in adults. Approved AL doses and dosing regimens include 441 …

Population pharmacokinetic analysis and model-based simulations of aripiprazole for a 1-day initiation regimen for the long-acting antipsychotic aripiprazole lauroxil

ML Hard, AY Wehr, BM Sadler, RJ Mills… - European journal of …, 2018 - Springer
Abstract Background and Objectives Aripiprazole lauroxil (AL), a long-acting injectable
antipsychotic for the treatment of schizophrenia, requires 21 days of oral aripiprazole …

Aripiprazole lauroxil: pharmacokinetic profile of this long-acting injectable antipsychotic in persons with schizophrenia

ML Hard, RJ Mills, BM Sadler, RZ Turncliff… - Journal of clinical …, 2017 - journals.lww.com
Background Aripiprazole lauroxil is an extended-release prodrug of aripiprazole for
intramuscular injection, approved for schizophrenia treatment. We developed a population …

Aripiprazole lauroxil: a review in schizophrenia

JE Frampton - Drugs, 2017 - Springer
Aripiprazole lauroxil long-acting injectable (LAI)[Aristada®] is an intramuscularly
administered, extended-release prodrug of aripiprazole, an established atypical …

Long-term safety and tolerability of aripiprazole lauroxil in patients with schizophrenia

HA Nasrallah, R Aquila, Y Du, AD Stanford… - CNS …, 2019 - cambridge.org
ObjectiveSafety and tolerability of long-term treatment with the long-acting antipsychotic
aripiprazole lauroxil (AL) were evaluated in patients with schizophrenia. MethodsThis was …

Pharmacokinetic evaluation of a 1-day treatment initiation option for starting long-acting aripiprazole lauroxil for schizophrenia

ML Hard, AY Wehr, Y Du, PJ Weiden… - Journal of Clinical …, 2018 - journals.lww.com
Background Aripiprazole lauroxil (AL), a long-acting injectable antipsychotic for the
treatment of schizophrenia, requires 21 days of oral aripiprazole supplementation upon …

Aripiprazole plasma concentrations delivered from two 2-month long-acting injectable formulations: an indirect comparison

M Harlin, C Chepke, F Larsen… - Neuropsychiatric …, 2023 - Taylor & Francis
Abstract Aripiprazole 2-month ready-to-use 960 mg (Ari 2MRTU 960) is a novel long-acting
injectable (LAI) formulation of aripiprazole monohydrate for administration once every 2 …

Pharmacokinetics and tolerability of intramuscular, oral and intravenous aripiprazole in healthy subjects and in patients with schizophrenia

DW Boulton, G Kollia, S Mallikaarjun… - Clinical …, 2008 - Springer
Background and objective: Patients with schizophrenia or bipolar disorder who are
experiencing acute behavioural emergencies often require intramuscular injection of …

Aripiprazole long-acting injectable formulations for schizophrenia: aripiprazole monohydrate and aripiprazole lauroxil

L Citrome - Expert review of clinical pharmacology, 2016 - Taylor & Francis
Aripiprazole monohydrate (AM) and aripiprazole lauroxil (AL) are two different long-acting
injectable formulations of aripiprazole. AM 400 mg administered once monthly demonstrated …