Biofilms are the primary cause of clinical bacterial infections and are impervious to typical
amounts of antibiotics, necessitating very high doses for elimination. Therefore, it is …

Microbial biofilms have caused serious concerns in healthcare, medical, and food industries
because of their intrinsic resistance against conventional antibiotics and cleaning …

Currently, three major circumstances threaten the management of bacterial infections:
increasing antimicrobial resistance, expansion of chronic biofilm-associated infections, and …

Biofilms form complex structures that are ubiquitous in natural environments and can cause
chronic infections which are difficult to treat. While much is known about biofilms, many …

Bacterial biofilms are the primary cause of infections in medical implants and catheters.
Delayed detection of biofilm infections contributes to the widespread use of high doses of …

The advent of microscale technologies, such as microfluidics, has revolutionized many
areas of biology yet has only recently begun to impact the field of bacterial biofilms. By …

Bacteria can attach to essentially all materials and form multicellular biofilms with high-level
tolerance to antimicrobials. Detrimental biofilms are responsible for a variety of problems …

We present the design, fabrication, and verification of a microfluidic platform for optical
monitoring of bacterial biofilms. Biofilm formation characterizes the majority of infections …

Highlights•We summarized current applications of systems biology approach on biofilm
investigation.•We summarized novel methods to detect biofilms.•We summarized novel …

Bacteria can form single-and multispecies biofilms exhibiting diverse features based upon
the microbial composition of their community and microenvironment. The study of bacterial …