The most definitive classification systems for dementia are based on the underlying
pathology which, in turn, is categorized largely according to the observed accumulation of …

The new guidelines provide a definition of the dementia syndrome and core diagnostic
features to be used in research and clinical practice, although they caution about the use of …

Neurodegenerative disorders are characterized by the formation of distinct pathological
changes in the brain, including extracellular protein deposits, cellular inclusions, and …

Neurodegenerative diseases are disorders characterized by progressive loss of neurons
associated with deposition of proteins showing altered physicochemical properties in the …

Dementia is an increasingly common diagnosis in our aging population, and the numbers
are expected to rise exponentially in coming years. Alzheimer's disease alone now affects …

Alzheimer's disease (AD) is the commonest neurodegenerative disease and the most
frequent cause of dementia. It affects 30 million people worldwide. Current research criteria …

Neuropathological diagnosis of neurodegenerative dementias evolved by adapting the
results of neuroanatomy, biochemistry, and cellular and molecular biology. Milestone …

The term dementia derives from the Latin root demens, which means being out of one's
mind. Although the term “dementia” has been used since the 13th century, its mention in the …

Accuracy of clinical diagnosis of dementia is increasingly important for therapeutic and
scientific investigations. In this study, we examine diagnostic accuracy in a consecutive …

Neurodegenerative diseases are characterised by selective dysfunction and progressive
loss of synapses and neurons associated with pathologically altered proteins that deposit …