The aim of epilepsy treatment is to achieve complete seizure freedom. Nonetheless,
numerous side effects and seizure resistance to antiepileptic drugs (AEDs) affecting about …

One third of the epilepsies are refractory to conventional antiepileptic drugs (AEDs) and,
therefore, identification of new therapies is highly needed. Here, we briefly describe two …

Gene therapy may constitute a promising alternative to conventional pharmacological tools
and surgeries for epilepsy. For primary epilepsy, a single variant leading to a significant …

The past decades have brought several advances to the treatment of epilepsy. However,
despite the continued development and release of new antiepileptic drugs (AEDs), more …

Epilepsy is a chronic non-infectious disease of the brain, characterized primarily by recurrent
unprovoked seizures, defined as an episode of disturbance of motor, sensory, autonomic, or …

Epilepsy is a common disabling chronic neurological disorder characterized by an enduring
propensity for the generation of seizures that result from abnormal hypersynchronous firing …

Epilepsy is a disorder of the central nervous system characterized by spontaneous recurrent
seizures. Although current therapies exist to control the number and severity of clinical …

Despite the immense growth of new anti-seizure drugs (ASDs), approximately one-third of
epilepsy patients remain resistant to current treatment options. Advancements in whole …

Gene therapy may represent an effective alternative to standard pharmacological
approaches for certain forms of epilepsy. Currently, the best candidates for this therapeutic …

Epilepsy is a major neurological disorder characterized by repeated seizures afflicting 1% of
the global population. The emergence of seizures is associated with several comorbidities …