Multidisciplinary expert opinion on the treatment consensus for patients with EGFR mutated NSCLC with brain metastases

S Ponce, J Bruna, O Juan, R López, A Navarro… - Critical reviews in …, 2019 - Elsevier
The presence of an epidermal growth factor receptor (EGFR) mutation is associated with
higher incidence of brain metastases in patients with non-small cell lung cancer (NSCLC); …

[HTML][HTML] A neuro-oncologist's perspective on management of brain metastases in patients with EGFR mutant non-small cell lung cancer

T McGranahan, S Nagpal - Current Treatment Options in Oncology, 2017 - Springer
Opinion statement Management of non-small cell lung cancer (NSCLC) with brain
metastasis (BrM) has been revolutionized by identification of molecular subsets that have …

[HTML][HTML] Treatment modes for EGFR mutations in patients with brain metastases from non-small cell lung cancer: controversy, causes, and solutions

H Zhuang, S Shi, JY Chang - Translational lung cancer research, 2019 - ncbi.nlm.nih.gov
Brain metastasis from non-small cell lung cancer (NSCLC) with epidermal growth factor
receptor (EGFR) mutations is a hot research topic, but also a difficulty in targeted NSCLC …

Commentary: treatment considerations for patients with epidermal growth factor receptor-mutated non-small cell lung cancer brain metastases in the era of tyrosine …

SD Vaca, ID Connolly, C Ho, J Neal, MH Gephart - Neurosurgery, 2018 - journals.lww.com
Brain metastasis is a serious complication of non-small cell lung cancer (NSCLC) affecting
up to 40% of NSCLC patients. A subset of NSCLC tumors has mutations in the epidermal …

Multiple treatment modalities for brain metastasis in patients with EGFR-mutant non-small-cell lung cancer

H Wang, X Yu, Y Fan, Y Jiang - OncoTargets and therapy, 2018 - Taylor & Francis
Background There are many controversies concerning the best management of epidermal
growth factor receptor (EGFR)-mutant non-small-cell lung cancer (NSCLC) patients with …

Real‐world utilization of EGFR TKIs and prognostic factors for survival in EGFR‐mutated non‐small cell lung cancer patients with brain metastases

X Yu, J Sheng, G Pan, Y Fan - International Journal of Cancer, 2021 - Wiley Online Library
Brain metastases (BMs) cause morbidity and mortality in patients with non‐small cell lung
cancer (NSCLC). The optimal management of epidermal growth factor receptor (EGFR) …

Paradigm shift of therapeutic management of brain metastases in EGFR-mutant non-small cell lung cancer in the era of targeted therapy

A Sekine, H Satoh - Medical Oncology, 2017 - Springer
Non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR)
mutations commonly present brain metastases (BM) at the time of NSCLC diagnosis or …

The optimal therapy strategy for epidermal growth factor receptor‐mutated non‐small cell lung cancer patients with brain metastasis: A real‐world study from Taiwan

WC Cheng, YC Shen, CR Chien, WC Liao… - Thoracic …, 2022 - Wiley Online Library
Background The treatment options for epidermal growth factor receptor (EGFR)‐mutated
non‐small cell lung cancer (NSCLC) with brain metastases (BMs) include EGFR‐tyrosine …

[HTML][HTML] Different Tyrosine Kinase Inhibitors Used in Treating EGFR-Mutant Pulmonary Adenocarcinoma with Brain Metastasis and Intracranial Intervention Have No …

CY Kuo, MJ Tsai, JY Hung, KL Wu, YM Tsai, YC Tsai… - Cancers, 2022 - mdpi.com
Simple Summary Brain metastasis is a factor of a poor prognosis in patients with non-small-
cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations …

Treatment outcomes of EGFR-TKI with or without locoregional brain therapy in advanced EGFR-mutant non-small cell lung cancer patients with brain metastases

TH Thinh, NV Hieu, NM Duc - Contemporary Oncology/Współczesna …, 2023 - termedia.pl
Results: Epidermal growth factor receptor tyrosine kinase inhibitor monotherapy patients
had better performance status (PS), fewer CNS symptoms, and significantly fewer brain …