Despite recent advances in the management of chronic kidney disease (CKD), morbidity
and mortality rates in these patients remain high. While pressure-mediated injury is a well …

Chronic kidney disease (CKD) is a chronic renal dysfunction syndrome that is characterized
by nephron loss, inflammation, myofibroblasts activation, and extracellular matrix (ECM) …

Oxidative stress and inflammation are mediators in the development and progression of
chronic kidney disease (CKD) and its complications, and they are inseparably linked as …

The nuclear factor erythroid 2-related factor 2 (Nrf2) protects the cell against oxidative
damage. The Nrf2 system comprises a complex network that functions to ensure adequate …

Oxidative stress and inflammation are constant features and major mediators of progression
of chronic kidney disease (CKD). Nuclear factor erythroid-2-related factor-2 (Nrf2) confers …

Inflammation and oxidative stress are two major components involved in the atherogenic
process generated by the innate immune response to lipoprotein peroxidation, which is …

Background Oxidative stress and inflammation are common features and the main
mediators of progression of chronic kidney disease (CKD) and its cardiovascular …

Chronic kidney disease (CKD) is featured by a progressive decline of kidney function and is
mainly caused by chronic diseases such as diabetes mellitus and hypertension. CKD is a …

Many types of kidney injury induce inflammation as a protective response. However,
unresolved inflammation promotes progressive renal fibrosis, which can culminate in end …

Renal fibrosis is a common fate of chronic kidney diseases. Emerging studies suggest that
unsolved inflammation will progressively transit into tissue fibrosis that finally results in an …