[HTML][HTML] Protective effects of Myrica rubra flavonoids against hypoxia/reoxygenation-induced cardiomyocyte injury via the regulation of the PI3K/Akt/GSK3β pathway

M Wang, Y Liu, RL Pan, RY Wang… - International …, 2019 - spandidos-publications.com
Myrica rubra is well known for its delicious taste and high nutritional value. The present
study investigated the potential protective effects and mechanisms of M. rubra flavonoids …

Myricitrin protects cardiomyocytes from hypoxia/reoxygenation injury: involvement of heat shock protein 90

M Wang, G Sun, Y Du, Y Tian, P Liao, X Liu… - Frontiers in …, 2017 - frontiersin.org
Modulation of oxidative stress is therapeutically effective in ischemia/reperfusion (I/R) injury.
Myricitrin, a naturally occurring phenolic compound, is a potent antioxidant. However, little is …

Oxymatrine pretreatment protects H9c2 cardiomyocytes from hypoxia/reoxygenation injury by modulating the PI3K/Akt pathway

Z Zhang, X Qin, Z Wang, Y Li… - Experimental and …, 2021 - spandidos-publications.com
Abstract Ischemia‑reperfusion (I/R) plays an important role in myocardial damage, which has
been widely recognized as a key procedure in the cardiovascular disease. A …

Picroside II inhibits hypoxia/reoxygenation-induced cardiomyocyte apoptosis by ameliorating mitochondrial function through a mechanism involving a decrease in …

JZ Li, SY Yu, D Mo, XN Tang… - … Journal of Molecular …, 2015 - spandidos-publications.com
Reactive oxygen species (ROS)-induced mitochondrial dysfunction plays an important role
in cardiomyocyte apoptosis during myocardial ischemia/reperfusion (I/R) injury. Picroside II …

Protective effects of myrrh essential oil on isoproterenol-induced myocardial infarction in rats through antioxidant, anti-inflammatory, Nrf2/HO-1 and apoptotic pathways

NS Younis, ME Mohamed - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Myrrh, a traditional remedy, is the stem resinous exudate
of Commiphora molmol Engler (Burseraceae). The aromatic yellowish-brown oleoresin has …

Protective effects of safranal on hypoxia/reoxygenation‑induced injury in H9c2 cardiac myoblasts via the PI3K/AKT/GSK3β signaling pathway

H Wang, B Zheng, K Che, X Han… - Experimental and …, 2021 - spandidos-publications.com
Safranal (SFR), an active ingredient extracted from saffron, exhibits a protective effect on the
cardiovascular system. However, the mechanism of SFR against hypoxia/reoxygenation …

Protective Effect and Mechanism of Total Flavones from Rhododendron simsii Planch Flower on Cultured Rat Cardiomyocytes with Anoxia and Reoxygenation

Y Jiao, YF Fan, YL Wang, JY Zhang… - Evidence‐Based …, 2015 - Wiley Online Library
Many flavonoids have cardioprotection against myocardial ischemia/reperfusion (I/R) injury.
Total flavones from Rhododendron simsii Planch flower (TFR) can protect myocardial …

[HTML][HTML] Resveratrol activates PI3K/AKT to reduce myocardial cell apoptosis and mitochondrial oxidative damage caused by myocardial ischemia/reperfusion injury

D Yu, J Xiong, Y Gao, J Li, D Zhu, X Shen, L Sun… - Acta …, 2021 - Elsevier
Resveratrol is a kind of iPolyphenols widely existing in herbal medicine. Here we aim to
investigate whether resveratrol can reduce the degree of myocardial ischemia/reperfusion …

[HTML][HTML] Gypenoside protects against myocardial ischemia-reperfusion injury by inhibiting cardiomyocytes apoptosis via inhibition of CHOP pathway and activation of …

H Yu, H Zhang, W Zhao, L Guo, X Li, Y Li… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Ischemia-reperfusion (I/R) injury is believed to be the major cause for
detriments in coronary heart diseases, but few effective therapies for prevention or treatment …

Cardioprotective effect of isorhamnetin against myocardial ischemia reperfusion (I/R) injury in isolated rat heart through attenuation of apoptosis

Y Xu, C Tang, S Tan, J Duan, H Tian… - Journal of Cellular and …, 2020 - Wiley Online Library
In this study, we investigated the effects of isorhamnetin on myocardial ischaemia
reperfusion (I/R) injury in Langendorff‐perfused rat hearts. Isorhamnetin treatment (5, 10 and …