Regenerative approaches for the treatment of large bone defects
A Stahl, YP Yang - Tissue Engineering Part B: Reviews, 2021 - liebertpub.com
A variety of engineered materials have gained acceptance in orthopedic practice as
substitutes for autologous bone grafts, although the regenerative efficacy of these …
substitutes for autologous bone grafts, although the regenerative efficacy of these …
Evolution of bone grafting: bone grafts and tissue engineering strategies for vascularized bone regeneration
KS Griffin, KM Davis, TO McKinley, JO Anglen… - Clinical reviews in bone …, 2015 - Springer
The regeneration of bone in segmental defects has historically been a challenge in the
orthopedic field. In particular, a lack of vascular supply often leads to nonunion and …
orthopedic field. In particular, a lack of vascular supply often leads to nonunion and …
Vascularization in bone tissue engineering constructs
ÁE Mercado-Pagán, AM Stahl, Y Shanjani… - Annals of biomedical …, 2015 - Springer
Vascularization of large bone grafts is one of the main challenges of bone tissue
engineering (BTE), and has held back the clinical translation of engineered bone constructs …
engineering (BTE), and has held back the clinical translation of engineered bone constructs …
Vascularized bone tissue engineering: approaches for potential improvement
Significant advances have been made in bone tissue engineering (TE) in the past decade.
However, classical bone TE strategies have been hampered mainly due to the lack of …
However, classical bone TE strategies have been hampered mainly due to the lack of …
Tissue engineering approaches for bone repair: concepts and evidence
JE Schroeder, R Mosheiff - Injury, 2011 - Elsevier
Over the last decades, the medical world has advanced dramatically in the understanding of
fracture repair. The three components needed for fracture healing are osteoconduction …
fracture repair. The three components needed for fracture healing are osteoconduction …
[HTML][HTML] Synthetic and Bone tissue engineering graft substitutes: What is the future?
RS Valtanen, YP Yang, GC Gurtner, WJ Maloney… - Injury, 2021 - Elsevier
The management of large segmental bone defects caused by trauma or disease remains
clinically challenging within orthopaedics. The major impediment to bone healing with …
clinically challenging within orthopaedics. The major impediment to bone healing with …
Skeletal regeneration for segmental bone loss: vascularised grafts, analogues and surrogates
B Dalisson, B Charbonnier, A Aoude, M Gilardino… - Acta Biomaterialia, 2021 - Elsevier
Massive segmental bone defects (SBD) are mostly treated by removing the fibula and
transplanting it complete with blood supply. While revolutionary 50 years ago, this remains …
transplanting it complete with blood supply. While revolutionary 50 years ago, this remains …
Review of vascularised bone tissue‐engineering strategies with a focus on co‐culture systems
Y Liu, JKY Chan, SH Teoh - Journal of tissue engineering and …, 2015 - Wiley Online Library
Poor angiogenesis within tissue‐engineered grafts has been identified as a main challenge
limiting the clinical introduction of bone tissue‐engineering (BTE) approaches for the repair …
limiting the clinical introduction of bone tissue‐engineering (BTE) approaches for the repair …
Bone regenerative medicine: classic options, novel strategies, and future directions
This review analyzes the literature of bone grafts and introduces tissue engineering as a
strategy in this field of orthopedic surgery. We evaluated articles concerning bone grafts; …
strategy in this field of orthopedic surgery. We evaluated articles concerning bone grafts; …
Biomaterial-mediated strategies targeting vascularization for bone repair
Repair of non-healing bone defects through tissue engineering strategies remains a
challenging feat in the clinic due to the aversive microenvironment surrounding the injured …
challenging feat in the clinic due to the aversive microenvironment surrounding the injured …