Outcomes of direct oral anticoagulants in atrial fibrillation patients across different body mass index categories

AF Barakat, S Jain, A Masri, L Alkukhun… - Clinical …, 2021 - jacc.org
Objectives This study sought to evaluate direct oral anticoagulant (DOAC) outcomes (vs.
warfarin) in patients with atrial fibrillation (AF) across body mass index (BMI) categories …

Efficacy and safety of direct oral anticoagulants versus warfarin in patients with atrial fibrillation across BMI categories: a systematic review and meta-analysis

Y Zhou, J Ma, W Zhu - American Journal of Cardiovascular Drugs, 2020 - Springer
Objectives Concerns have arisen recently over the relationship between body mass index
(BMI) and outcomes in atrial fibrillation (AF) patients with direct oral anticoagulants (DOACs) …

Comparative effectiveness and safety of direct oral anticoagulants in obese patients with atrial fibrillation

A Briasoulis, A Mentias, A Mazur, P Alvarez… - … drugs and therapy, 2021 - Springer
Background Unlike warfarin direct oral anticoagulants (DOACs) are administered in fixed
doses, which raises concerns of its effectiveness on larger patients. Data from randomized …

Patients with higher body mass index treated with direct/novel oral anticoagulants (DOAC/NOAC) for atrial fibrillation experience worse clinical outcomes

M Lucijanic, I Jurin, H Jurin, T Lucijanic… - International journal of …, 2020 - Elsevier
Introduction Due to fixed dosing of direct oral anticoagulants (DOACs), uncertainty exists
about their efficacy in a population of obese/overweight patients. Patients and methods We …

Direct oral anticoagulants in patients with nonvalvular atrial fibrillation and low body weight

SR Lee, EK Choi, CS Park, KD Han, JH Jung… - Journal of the American …, 2019 - jacc.org
Background: It is unclear whether the overall effectiveness and safety of direct oral
anticoagulants (DOACs) are consistent in patients with nonvalvular atrial fibrillation (AF) and …

Efficacy and safety of direct oral anticoagulants for atrial fibrillation across body mass index categories

RM Kaplan, Y Tanaka, RS Passman… - Journal of the …, 2020 - Am Heart Assoc
Background Direct‐acting oral anticoagulants are now the preferred method of
anticoagulation in patients with atrial fibrillation. Limited data on efficacy and safety of these …

Inappropriate dosing of direct oral anticoagulants in patients with atrial fibrillation

A Sugrue, D Sanborn, M Amin, M Farwati… - The American journal of …, 2021 - Elsevier
Direct Oral Anticoagulants (DOACs) require dose adjustment based on specific patient
characteristics, making them prone to incorrect dosing. The current study aimed to evaluate …

Impact of weight on the efficacy and safety of direct-acting oral anticoagulants in patients with non-valvular atrial fibrillation: a meta-analysis

AH Malik, S Yandrapalli, S Shetty, WS Aronow… - EP …, 2020 - academic.oup.com
Aims This study sought to determine the impact of weight and body mass index (BMI) on the
safety and efficacy of direct-acting oral anticoagulants (DOACs) compared with warfarin in …

Evaluation of safety and efficacy outcomes of direct oral anticoagulants versus warfarin in normal and extreme body weights for the treatment of atrial fibrillation or …

AR Novak, C Shakowski, TC Trujillo, GC Wright… - Journal of Thrombosis …, 2022 - Springer
Despite evolving evidence, the use of direct oral anticoagulants (DOACs) in patients with
extremes of body weight remains controversial. This study aimed to measure the impact of …

Prescription patterns and outcomes of patients with atrial fibrillation treated with direct oral anticoagulants and warfarin: a real-world analysis

AJ Kattoor, NV Pothineni, A Goel… - Journal of …, 2019 - journals.sagepub.com
Background: Direct oral anticoagulants (DOACs) have been found to be similar or superior
to warfarin in reducing ischemic stroke and intracranial hemorrhage (ICH) in patients with …