Treatment of uterine fibroid symptoms with relugolix combination therapy
A Al-Hendy, AS Lukes, AN Poindexter III… - … England Journal of …, 2021 - Mass Medical Soc
Background Uterine fibroids are a common cause of heavy menstrual bleeding and pain.
Treatment with the combination of relugolix (an oral gonadotropin-releasing hormone …
Treatment with the combination of relugolix (an oral gonadotropin-releasing hormone …
[HTML][HTML] Relugolix, a novel oral gonadotropin-releasing hormone antagonist, in the treatment of pain symptoms associated with uterine fibroids: a randomized, placebo …
Y Osuga, K Enya, K Kudou, H Hoshiai - Fertility and sterility, 2019 - Elsevier
Objective To investigate the efficacy and safety of the oral gonadotropin-releasing hormone
receptor antagonist, relugolix, in patients experiencing uterine fibroid–associated pain …
receptor antagonist, relugolix, in patients experiencing uterine fibroid–associated pain …
Elagolix for heavy menstrual bleeding in women with uterine fibroids
WD Schlaff, RT Ackerman, A Al-Hendy… - … England Journal of …, 2020 - Mass Medical Soc
Background Uterine fibroids are hormone-responsive neoplasms that are associated with
heavy menstrual bleeding. Elagolix, an oral gonadotropin-releasing hormone antagonist …
heavy menstrual bleeding. Elagolix, an oral gonadotropin-releasing hormone antagonist …
[HTML][HTML] Elagolix for the management of heavy menstrual bleeding associated with uterine fibroids: results from a phase 2a proof-of-concept study
DF Archer, EA Stewart, RI Jain, RA Feldman… - Fertility and sterility, 2017 - Elsevier
Objective To evaluate the safety and efficacy of elagolix vs. placebo and elagolix with low-
dose E 2/progestogen add-back therapy. Design Proof-of-concept, dose-ranging, multiple …
dose E 2/progestogen add-back therapy. Design Proof-of-concept, dose-ranging, multiple …
Linzagolix with and without hormonal add-back therapy for the treatment of symptomatic uterine fibroids: two randomised, placebo-controlled, phase 3 trials
J Donnez, HS Taylor, EA Stewart, L Bradley, E Marsh… - The Lancet, 2022 - thelancet.com
Background Uterine fibroids are common non-cancerous neoplasm that cause heavy
menstrual bleeding and other signs. Linzagolix is an oral gonadotropin-releasing hormone …
menstrual bleeding and other signs. Linzagolix is an oral gonadotropin-releasing hormone …
Ulipristal acetate versus leuprolide acetate for uterine fibroids
J Donnez, J Tomaszewski, F Vázquez… - … England Journal of …, 2012 - Mass Medical Soc
Background The efficacy and side-effect profile of ulipristal acetate as compared with those
of leuprolide acetate for the treatment of symptomatic uterine fibroids before surgery are …
of leuprolide acetate for the treatment of symptomatic uterine fibroids before surgery are …
[HTML][HTML] Current medical treatment of uterine fibroids
GS Sohn, SH Cho, YM Kim, CH Cho… - Obstetrics & …, 2018 - synapse.koreamed.org
Uterine fibroids (leiomyomas or myomas), benign monoclonal tumors, are the most common
benign tumors in women. Heavy or prolonged menstrual bleeding, abnormal uterine …
benign tumors in women. Heavy or prolonged menstrual bleeding, abnormal uterine …
[HTML][HTML] Long-term treatment of uterine fibroids with ulipristal acetate☆
J Donnez, F Vázquez, J Tomaszewski, K Nouri… - Fertility and sterility, 2014 - Elsevier
Objective To investigate the efficacy and safety of ulipristal acetate (UPA) for long-term
treatment of symptomatic uterine fibroids. Design Repeated intermittent open-label UPA …
treatment of symptomatic uterine fibroids. Design Repeated intermittent open-label UPA …
[HTML][HTML] Conservative management of uterine fibroid-related heavy menstrual bleeding and infertility: time for a deeper mechanistic understanding and an …
MM Dolmans, L Cacciottola, J Donnez - Journal of clinical medicine, 2021 - mdpi.com
(1) Background: Uterine fibroids are the most common form of benign uterine tumors,
causing heavy menstrual bleeding (HMB), pelvic pain, infertility and pressure symptoms …
causing heavy menstrual bleeding (HMB), pelvic pain, infertility and pressure symptoms …
Ulipristal acetate: a novel pharmacological approach for the treatment of uterine fibroids
N Biglia, S Carinelli, A Maiorana… - Drug design …, 2014 - Taylor & Francis
Uterine fibroids are the most common benign tumors of the female genital tract. The
management of symptomatic fibroids has traditionally been surgical; however, alternative …
management of symptomatic fibroids has traditionally been surgical; however, alternative …