[HTML][HTML] Application of a Novel Proteomic Microarray Reveals High Exposure to Diarrhoeagenic Escherichia coli among Children in Zambia Participating in a Phase I …
Diarrhoeagenic E. coli (DEC) significantly contributes to the burden of diarrhoea among
children. Currently, there is no approved vaccine against DEC, but several vaccines against …
children. Currently, there is no approved vaccine against DEC, but several vaccines against …
Epidemiology of Enteroaggregative, Enteropathogenic, and Shiga Toxin–Producing Escherichia coli Among Children Aged <5 Years in 3 Countries in Africa, 2015 …
JB Ochieng, H Powell, CE Sugerman… - Clinical Infectious …, 2023 - academic.oup.com
Background To address knowledge gaps regarding diarrheagenic Escherichia coli (DEC) in
Africa, we assessed the clinical and epidemiological features of enteroaggregative E. coli …
Africa, we assessed the clinical and epidemiological features of enteroaggregative E. coli …
[HTML][HTML] Safety, tolerability, and immunogenicity of an oral inactivated ETEC vaccine (ETVAX®) with dmLT adjuvant in healthy adults and children in Zambia: An age …
N Sukwa, C Mubanga, LM Hatyoka… - Vaccine, 2023 - Elsevier
Abstract Background Enterotoxigenic Escherichia coli (ETEC) is an important cause of
moderate to severe diarrhoea in children for which there is no licensed vaccine. We …
moderate to severe diarrhoea in children for which there is no licensed vaccine. We …
A Perspective on the Strategy for Advancing ETVAX®, An Anti-ETEC Diarrheal Disease Vaccine, into a Field Efficacy Trial in Gambian Children: Rationale …
MJ Hossain, AM Svennerholm, N Carlin… - Microorganisms, 2023 - mdpi.com
For the first time in over 20 years, an Enterotoxigenic Escherichia coli (ETEC) vaccine
candidate, ETVAX®, has advanced into a phase 2b field efficacy trial for children 6–18 …
candidate, ETVAX®, has advanced into a phase 2b field efficacy trial for children 6–18 …
Defining cases of severe pediatric diarrhea for an efficacy trial of an enterotoxigenic Escherichia coli (ETEC) vaccine: report on an international workshop, Washington …
TF Wierzba, A Bourgis - Vaccine, 2017 - Elsevier
Enterotoxigenic Escherichia coli (ETEC) causes severe acute watery diarrhea. No ETEC
vaccine is available but candidates are in development, including ETVAX, an oral, whole …
vaccine is available but candidates are in development, including ETVAX, an oral, whole …
[HTML][HTML] Site specific incidence rate of genomic subtypes of enteropathogenic Escherichia coli and association with enteric inflammation and child growth
There is a lack of information highlighting the possible association between the genomic
subtypes of enteropathogenic Escherichia coli (EPEC) on environmental enteric dysfunction …
subtypes of enteropathogenic Escherichia coli (EPEC) on environmental enteric dysfunction …
[HTML][HTML] Prevalence of Diarrhoeagenic Escherichia coli among Children Aged between 0–36 Months in Peri-Urban Areas of Lusaka
Diarrhoea is a major contributor to childhood morbidity and mortality in developing
countries, with diarrhoeagenic Escherichia coli being among the top aetiological agents. We …
countries, with diarrhoeagenic Escherichia coli being among the top aetiological agents. We …
[HTML][HTML] Molecular characterization of diarrheagenic Escherichia coli isolates from children with diarrhea: A cross-sectional study in four provinces of Mozambique …
L Manhique-Coutinho, P Chiani, V Michelacci… - International Journal of …, 2022 - Elsevier
Objectives Analyze the frequency of diarrheagenic Escherichia coli (DEC) pathotypes and
their antimicrobial resistance profiles among children aged< 15 years with diarrhea in four …
their antimicrobial resistance profiles among children aged< 15 years with diarrhea in four …
[HTML][HTML] Risk factors for diarrheagenic Escherichia coli infection in children aged 6–24 months in peri-urban community, Nairobi, Kenya
Escherichia coli commonly inhabits the gut of humans and animals as part of their
microbiota. Though mostly innocuous, some strains have virulence markers that make them …
microbiota. Though mostly innocuous, some strains have virulence markers that make them …
[HTML][HTML] Identification of subsets of enteroaggregative Escherichia coli associated with diarrheal disease among under 5 years of age children from Rural Gambia
UN Ikumapayi, N Boisen, MJ Hossain… - The American journal …, 2017 - ncbi.nlm.nih.gov
Enteroaggregative Escherichia coli (EAEC) cause acute and persistent diarrhea, mostly in
children worldwide. Outbreaks of diarrhea caused by EAEC have been described, including …
children worldwide. Outbreaks of diarrhea caused by EAEC have been described, including …
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