Native mass spectrometry-based metabolomics identifies metal-binding compounds
Although metals are essential for the molecular machineries of life, systematic methods for
discovering metal–small molecule complexes from biological samples are limited. Here, we …
discovering metal–small molecule complexes from biological samples are limited. Here, we …
ChelomEx: isotope-assisted discovery of metal chelates in complex media using high-resolution LC-MS
Chelating agents can control the speciation and reactivity of trace metals in biological,
environmental, and laboratory-derived media. A large number of trace metals (including Fe …
environmental, and laboratory-derived media. A large number of trace metals (including Fe …
MetabNet: an R package for metabolic association analysis of high-resolution metabolomics data
K Uppal, QA Soltow, DEL Promislow… - … in bioengineering and …, 2015 - frontiersin.org
Liquid-chromatography high-resolution mass spectrometry provides capability to measure>
40,000 ions derived from metabolites in biologic samples. This presents challenges to …
40,000 ions derived from metabolites in biologic samples. This presents challenges to …
Metalloproteomics for biomedical research: methodology and applications
Metals are essential components in life processes and participate in many important
biological processes. Dysregulation of metal homeostasis is correlated with many diseases …
biological processes. Dysregulation of metal homeostasis is correlated with many diseases …
A positive/negative ion–switching, targeted mass spectrometry–based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue
M Yuan, SB Breitkopf, X Yang, JM Asara - Nature protocols, 2012 - nature.com
The revival of interest in cancer cell metabolism in recent years has prompted the need for
quantitative analytical platforms for studying metabolites from in vivo sources. We …
quantitative analytical platforms for studying metabolites from in vivo sources. We …
ReDU: a framework to find and reanalyze public mass spectrometry data
Abstract We present ReDU (https://redu. ucsd. edu/), a system for metadata capture of public
mass spectrometry-based metabolomics data, with validated controlled vocabularies …
mass spectrometry-based metabolomics data, with validated controlled vocabularies …
[PDF][PDF] Identification of metal-associated proteins in cells by using continuous-flow gel electrophoresis and inductively coupled plasma mass spectrometry
L Hu, T Cheng, B He, L Li, Y Wang, YT Lai… - Angew. Chem. Int …, 2013 - core.ac.uk
Metals and metalloids are crucial for life and indispensable for a series of biological
processes.[1] It is estimated that a quarter to one third of all proteins require metals to carry …
processes.[1] It is estimated that a quarter to one third of all proteins require metals to carry …
Discovery of metal-binding proteins by thermal proteome profiling
X Zeng, T Wei, X Wang, Y Liu, Z Tan, Y Zhang… - Nature Chemical …, 2024 - nature.com
Metal-binding proteins (MBPs) have various and important biological roles in all living
species and many human diseases are intricately linked to dysfunctional MBPs. Here, we …
species and many human diseases are intricately linked to dysfunctional MBPs. Here, we …
Elemental tagging in inorganic mass spectrometric bioanalysis
J Bettmer, N Jakubowski, A Prange - Analytical and bioanalytical chemistry, 2006 - Springer
We want to point out that new developments seen in proteomics are very similar to a well-
established trend in the analytical applications of inductively coupled plasmamass …
established trend in the analytical applications of inductively coupled plasmamass …
xMSannotator: an R package for network-based annotation of high-resolution metabolomics data
Improved analytical technologies and data extraction algorithms enable detection of> 10
000 reproducible signals by liquid chromatography–high-resolution mass spectrometry …
000 reproducible signals by liquid chromatography–high-resolution mass spectrometry …