Mechanisms of estrogen action

S Nilsson, S Makela, E Treuter… - Physiological …, 2001 - journals.physiology.org
Our appreciation of the physiological functions of estrogens and the mechanisms through
which estrogens bring about these functions has changed during the past decade. Just as …

Estrogen receptors: new directions in the new millennium

SC Hewitt, KS Korach - Endocrine reviews, 2018 - academic.oup.com
Nineteen years have passed since our previous review in this journal in 1999 regarding
estrogen receptors. At that time, we described the current assessments of the physiological …

Role of estrogen receptor beta in estrogen action

K Pettersson, JÅ Gustafsson - Annual review of physiology, 2001 - annualreviews.org
▪ Abstract There was a time when the classification of sex hormones was simple. Androgens
were male and estrogens female. What remains true today is that in young adults androgen …

Estrogen receptors: bioactivities and interactions with cell signaling pathways

BS Katzenellenbogen - Biology of reproduction, 1996 - academic.oup.com
Estrogens regulate the growth, differentiation, and functioning of diverse target tissues, both
within and outside of the reproductive system. Most of the actions of estrogens appear to be …

Connections and regulation of the human estrogen receptor

DP McDonnell, JD Norris - Science, 2002 - science.org
Estrogen regulates a plethora of functionally dissimilar processes in a broad range of
tissues. Recent progress in the study of the molecular mechanism of action of estrogen (s) …

Mechanisms of action and cross-talk between estrogen receptor and progesterone receptor pathways

BS Katzenellenbogen - The Journal of the Society for Gynecologic …, 2000 - Springer
The intriguing biology of estrogens and progestins in their diverse target cells is determined
by the structure of the hormonal ligand, the receptor subtype or isoform involved, the nature …

Estrogen receptors: structure, mechanisms and function

SC Hewitt, KS Korach - Reviews in Endocrine and Metabolic Disorders, 2002 - Springer
The biological effects of estrogen (E) in mammalian target tissues are important for
numerous physiological processes. E is known to induce responses in the reproductive tract …

Estrogen receptor signaling mechanisms

N Fuentes, P Silveyra - Advances in protein chemistry and structural …, 2019 - Elsevier
The primary female sex hormones, estrogens, are responsible for the control of functions of
the female reproductive system, as well as the development of secondary sexual …

Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology

BS Katzenellenbogen, I Choi… - The Journal of steroid …, 2000 - Elsevier
Estrogens exert profound effects on the physiology of diverse target cells and these effects
appear to be mediated by two estrogen receptor (ER) subtypes, ERα and ERβ. We have …

Estrogen receptor interaction with co-activators and co-repressors☆

CM Klinge - Steroids, 2000 - Elsevier
Estrogens exert a wide variety of effects on growth, development, and differentiation,
including important regulatory functions within the reproductive systems of both females and …