[HTML][HTML] Contribution to the Synthesis, Characterization, Separation and Quantification of New N-Acyl Thiourea Derivatives with Antimicrobial and Antioxidant …

R Roman, L Pintilie, DC Nuță, MT Căproiu… - Pharmaceutics, 2023 - mdpi.com
The present study aimed to synthesize, characterize, and validate a separation and
quantification method of new N-acyl thiourea derivatives (1a–1o), incorporating thiazole or …

[HTML][HTML] New N-acyl Thiourea Derivatives: Synthesis, Standardized Quantification Method and In Vitro Evaluation of Potential Biological Activities

R Roman, L Pintilie, MT Căproiu, F Dumitrașcu… - Antibiotics, 2023 - mdpi.com
New N-acyl thiourea derivatives with heterocyclic rings have been synthesized by first
obtaining isothiocyanate, which further reacted with a heterocyclic amine, characterized by …

[HTML][HTML] Synthesis and characterization of new fluoro/trifluoromethyl-substituted acylthiourea derivatives with promising activity against planktonic and biofilm …

C Limban, DC Nuta, AV Missir, R Roman, MT Caproiu… - Processes, 2020 - mdpi.com
The aim of this study was preparation of new derivatives based on 2-((4-chlorophenoxy)
methyl)-N-(arylcarbamothioyl) benzamide structure; the new compounds were characterized …

Design, synthesis, characterization, and biological evaluation of nicotinoyl thioureas as antimicrobial and antioxidant agents

B Özgeriş - The Journal of Antibiotics, 2021 - nature.com
Addressed herein a series of thioureas starting from various amines and nicotinic acid have
been synthesized. Notably, thiourea based scaffolds are increasingly employed in medicinal …

SYNTHESIS, STRUCTURAL, PHISICO-CHEMICAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY SCREENING OF NEW THIOUREA DERIVATIVES.

CD BĂDICEANU, DC NUȚĂ, AV MISSIR… - …, 2018 - search.ebscohost.com
A number of seven new thiourea derivatives having thiophene skeleton, obtained from 2-
thiopheneacetic acid, have been synthesized, characterized by their physical properties …

Antimicrobial and anti-biofilm activity of thiourea derivatives bearing 3-amino-1H-1, 2, 4-triazole scaffold

J Stefanska, K Stepien, A Bielenica… - Medicinal …, 2016 - ingentaconnect.com
A set of 21 thiourea derivatives were prepared through reacting 3-amino-1H-1, 2, 4-triazole
with the commercial aliphatic and aromatic isothiocyanates. The aliphatic isothiocyanate …

Design, one-pot synthesis, in silico ADMET prediction and molecular docking of novel triazolyl thiadiazine and thiazole derivatives with evaluation of antimicrobial …

RE Khidre, E Sabry, AF El-Sayed, AA Sediek - Journal of the Iranian …, 2023 - Springer
A facile one pot multi-component synthesis of novel 1, 3, 4-thiadiazine and thiazole
derivatives from the reaction of (methyl-1-(p-tolyl)-1 H-1, 2, 3-triazol-4-yl) ethan-1-one …

[HTML][HTML] Synthesis, spectroscopic properties and antipathogenic activity of new thiourea derivatives

C Limban, L Marutescu, MC Chifiriuc - Molecules, 2011 - mdpi.com
A number of acylthioureas, 2-((4-methylphenoxy) methyl)-N-(aryl-carbamothioyl)
benzamides (aryl= 3, 5-dichlorophenyl, 2, 3-dichlorophenyl, 3, 4-dichloro-phenyl, 2, 4, 5 …

Synthesis, biological evaluation and in silico study of bis-thiourea derivatives as anticancer, antimalarial and antimicrobial agents

R Pingaew, N Sinthupoom, P Mandi… - Medicinal Chemistry …, 2017 - Springer
Two sets of bis-thioureas including a para series (8–14) and a meta series (4, 5, 15–19),
were synthesized and evaluated for their anticancer, antimalarial and antimicrobial activities …

[HTML][HTML] Antioxidant and antibacterial activities of 5-mercapto (substitutedthio)-4-substituted-1, 2, 4-triazol based on nalidixic acid: A comprehensive study on its …

I Mhaidat, S Banidomi, F Wedian, R Badarneh… - Heliyon, 2024 - cell.com
This study introduces a series of novel Alkyl thio-1, 2, 4-triazole (4a-p) and mercapto-1, 2, 4-
triazole (3a-d) compounds derived from nalidixic acid. The synthesis was streamlined …