The inflammatory lung microenvironment; a key mediator in MSC licensing
H Dunbar, DJ Weiss, S Rolandsson Enes, JG Laffey… - Cells, 2021 - mdpi.com
Recent clinical trials of mesenchymal stromal cell (MSC) therapy for various inflammatory
conditions have highlighted the significant benefit to patients who respond to MSC …
conditions have highlighted the significant benefit to patients who respond to MSC …
Healthy versus inflamed lung environments differentially affect mesenchymal stromal cells
SR Enes, TH Hampton, J Barua… - European …, 2021 - Eur Respiratory Soc
Background Despite increased interest in mesenchymal stromal cell (MSC)-based cell
therapies for acute respiratory distress syndrome (ARDS), clinical investigations have not yet …
therapies for acute respiratory distress syndrome (ARDS), clinical investigations have not yet …
Research progress on strategies that can enhance the therapeutic benefits of mesenchymal stromal cells in respiratory diseases with a specific focus on acute …
S Rolandsson Enes, AD Krasnodembskaya… - Frontiers in …, 2021 - frontiersin.org
Recent advances in cell based therapies for lung diseases and critical illnesses offer
significant promise. Despite encouraging preclinical results, the translation of efficacy to the …
significant promise. Despite encouraging preclinical results, the translation of efficacy to the …
[HTML][HTML] Recent insights: mesenchymal stromal/stem cell therapy for acute respiratory distress syndrome
S Horie, JG Laffey - F1000Research, 2016 - ncbi.nlm.nih.gov
Acute respiratory distress syndrome (ARDS) causes respiratory failure, which is associated
with severe inflammation and lung damage and has a high mortality and for which there is …
with severe inflammation and lung damage and has a high mortality and for which there is …
Therapeutic potential and mechanisms of action of mesenchymal stromal cells for acute respiratory distress syndrome
Mesenchymal stem/stromal cells (MSCs) have become the focus of intense research effort
over the past 10 years, in an effort to harness their regenerative and immune-modulating …
over the past 10 years, in an effort to harness their regenerative and immune-modulating …
Cell therapy for lung disease: current status and future prospects
S Rolandsson Enes, DJ Weiss - Current Stem Cell Reports, 2020 - Springer
Abstract Purpose of Review Mesenchymal stromal cell (MSC)–based therapies provide a
platform for new therapeutic strategies in lung diseases. This review provides an overview of …
platform for new therapeutic strategies in lung diseases. This review provides an overview of …
MSCs interaction with the host lung microenvironment: An overlooked aspect?
DJ Weiss, S Rolandsson Enes - Frontiers in Immunology, 2022 - frontiersin.org
Mesenchymal stromal cells (MSCs) were identified more than 50 years ago, and research
advances have promoted the translation of pre-clinical studies into clinical settings in …
advances have promoted the translation of pre-clinical studies into clinical settings in …
Cell-based Therapies for Acute Respiratory Distress Syndrome: Where Are We Now?
GF Curley, CM O'Kane, DF McAuley… - American Journal of …, 2024 - atsjournals.org
There is considerable interest in the potential for cell-based therapies, particularly
mesenchymal stromal cells (MSCs) and their products, as a therapy for acute respiratory …
mesenchymal stromal cells (MSCs) and their products, as a therapy for acute respiratory …
In vivo effects of mesenchymal stromal cells in two patients with severe acute respiratory distress syndrome
OE Simonson, D Mougiakakos… - Stem cells …, 2015 - academic.oup.com
Mesenchymal stromal cells (MSCs) have been investigated as a treatment for various
inflammatory diseases because of their immunomodulatory and reparative properties …
inflammatory diseases because of their immunomodulatory and reparative properties …
Current understanding of the therapeutic benefits of mesenchymal stem cells in acute respiratory distress syndrome
M Lopes-Pacheco, C Robba, PRM Rocco… - Cell biology and …, 2020 - Springer
The acute respiratory distress syndrome (ARDS) is a multifaceted lung disorder in which no
specific therapeutic intervention is able to effectively improve clinical outcomes. Despite an …
specific therapeutic intervention is able to effectively improve clinical outcomes. Despite an …