Microfluidics for cell separation

AAS Bhagat, H Bow, HW Hou, SJ Tan, J Han… - Medical & biological …, 2010 - Springer
The need for efficient cell separation, an essential preparatory step in many biological and
medical assays, has led to the recent development of numerous microscale separation …

Large-volume microfluidic cell sorting for biomedical applications

ME Warkiani, L Wu, AKP Tay… - Annual review of …, 2015 - annualreviews.org
Microfluidic cell-separation technologies have been studied for almost two decades, but the
limited throughput has restricted their impact and range of application. Recent advances in …

Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation

CW Shields Iv, CD Reyes, GP López - Lab on a Chip, 2015 - pubs.rsc.org
Accurate and high throughput cell sorting is a critical enabling technology in molecular and
cellular biology, biotechnology, and medicine. While conventional methods can provide high …

Continuous separation of cells and particles in microfluidic systems

A Lenshof, T Laurell - Chemical Society Reviews, 2010 - pubs.rsc.org
The progress in microfabrication and lab-on-a-chip technologies has been a major area of
development for new approaches to bioanalytics and integrated concepts for cell biology …

Microfluidic blood cell sorting: now and beyond

ZTF Yu, KM Aw Yong, J Fu - Small, 2014 - Wiley Online Library
Blood plays an important role in homeostatic regulation with each of its cellular components
having important therapeutic and diagnostic uses. Therefore, separation and sorting of …

Blood-on-a-chip

M Toner, D Irimia - Annu. Rev. Biomed. Eng., 2005 - annualreviews.org
▪ Abstract Accurate, fast, and affordable analysis of the cellular component of blood is of
prime interest for medicine and research. Yet, most often sample preparation procedures for …

Translating microfluidics: Cell separation technologies and their barriers to commercialization

CW Shields IV, KA Ohiri, LM Szott… - Cytometry Part B …, 2017 - Wiley Online Library
Advances in microfluidic cell sorting have revolutionized the ways in which cell‐containing
fluids are processed, now providing performances comparable to, or exceeding, traditional …

Microfluidic devices for blood fractionation

HW Hou, AAS Bhagat, WC Lee, S Huang, J Han… - Micromachines, 2011 - mdpi.com
Blood, a complex biological fluid, comprises 45% cellular components suspended in protein
rich plasma. These different hematologic components perform distinct functions in vivo and …

A review of sorting, separation and isolation of cells and microbeads for biomedical applications: microfluidic approaches

A Dalili, E Samiei, M Hoorfar - Analyst, 2019 - pubs.rsc.org
Several biomedical analyses are performed on particular types of cells present in body
samples or using functionalized microparticles. Success in such analyses depends on the …

Blood cells separation and sorting techniques of passive microfluidic devices: From fabrication to applications

SO Catarino, RO Rodrigues, D Pinho, JM Miranda… - Micromachines, 2019 - mdpi.com
Since the first microfluidic device was developed more than three decades ago, microfluidics
is seen as a technology that exhibits unique features to provide a significant change in the …