Microsatellite instability (MSI) characterizes colorectal carcinomas (CRCs) in hereditary
nonpolyposis colorectal cancer (HNPCC) syndrome and a proportion of sporadic CRCs …

Colorectal cancers with high-frequency microsatellite instability show peculiar
clinicopathological features and a favorable clinical outcome. We investigated whether the …

Cancer with high levels of microsatellite instability (MSI-H) is the hallmark of hereditary
nonpolyposis colorectal cancer syndrome, and MSI-H occurs in∼ 15% of sporadic …

Background Patients with colorectal cancer that display high-level microsatellite instability
(MSI-H) appear to have a better prognosis. This may be explained by the pronounced T cell …

Sporadic or hereditary colorectal cancer (CRC) with microsatellite instability (MSI) is
frequently characterized by inflammatory lymphocytic infiltration and tends to be associated …

The phenotypic markers of colorectal carcinomas with microsatellite instability have been
widely studied and include mucinous or poor differentiation, prominent host response, a …

Background: A recent clinical trial on the immune check-point inhibitor pembrolizumab
demonstrated that microsatellite instability (MSI) is a good biomarker for response to this …

Colorectal cancers with microsatellite instability (MSI) typically show increased numbers of
intraepithelial lymphocytes (IEL) in comparison to microsatellite stable (MSS) cancers. The …

Identification of microsatellite unstable (MSI-H) colorectal cancers (CRCs) is important not
only for the identification of hereditary nonpolyposis colorectal cancer syndrome but also …

Colorectal carcinomas (CRCs) with high microsatellite instability (MSI-H) share
clinicopathological features distinctly different from their microsatellite stable (MSS) …