African ancestry is a significant risk factor for prostate cancer and advanced disease. Yet,
genetic studies have largely been conducted outside the context of Sub-Saharan Africa …

Abstract Background Although African ancestry represents a significant risk factor for
prostate cancer, few studies have investigated the significance of prostate cancer and …

In search of common risk alleles for prostate cancer that could contribute to high rates of the
disease in men of African ancestry, we conducted a genome-wide association study, with …

Backgrounds Genetic diversity is greatest within Africa, in particular the KhoeSan click-
speaking peoples of southern Africa. South African populations represent admixture …

Background Men of African‐ancestry have elevated prostate cancer (PCa) incidence and
mortality compared to men of other racial groups. There is support for a genetic contribution …

Prostate cancer incidence and mortality rates in African and African American men are
greatly elevated compared with other ethnicities. This disparity is likely explained by a …

Prostate cancer (PCa) is a significant health burden in Sub-Saharan Africa, with mortality
rates loosely linked to African ancestry. Yet studies aimed at identifying contributing risk …

Background We previously developed an African-ancestry-specific polygenic hazard score
(PHS46+ African) that substantially improved prostate cancer risk stratification in men with …

Genome‐wide association studies have identified more than 80 risk variants for prostate
cancer, mainly in European or Asian populations. The generalizability of these variants in …

GWAS of prostate cancer have been remarkably successful in revealing common genetic
variants and novel biological pathways that are linked with its etiology. A more complete …