Innovations in next-generation sequencing technology have introduced new avenues in
microbial studies through “omics” approaches. This technology has considerably …

Highlights•Phages are abundant within ecosystems, but their role is often understated.•
Ecological success models can help explain observed phage–bacteria …

The basic biology of bacteriophage–host interactions has attracted increasing attention due
to a renewed interest in the therapeutic potential of bacteriophages. In addition, knowledge …

Since their discovery, bacteriophages have been traditionally regarded as the natural
enemies of bacteria. However, recent advances in molecular biology techniques, especially …

Bacteria and their viruses (phages) are abundant across diverse ecosystems and their
interactions influence global biogeochemical cycles and incidence of disease …

Emerging and reemerging bacterial infectious diseases are a major public health concern
worldwide. The role of bacteriophages in the emergence of novel bacterial pathogens by …

alexander sulakvelidze intralytix, inc.; Baltimore, Md Usa classification of bacteriophages;(2)
phage genomics and evolution;(3) molecular mechanisms of phage infection, including but …

Highlights•Phage-encoded receptor-binding proteins can be used to isolate host
strains.•Protein structure prediction is useful in identifying receptor types.•Hi-C sequencing is …

Introduction The mounting incidence of multidrug-resistant bacterial strains and the dearth of
novel antibiotics demand alternate therapies to manage the infections caused by resistant …

Studying the coevolutionary dynamics between bacteria and the bacteriophage viruses that
infect them is critical to understanding both microbial diversity and ecosystem functioning …