Despite the knowledge that women are more susceptible than men to stress-related mental
illness, such as major depression, there is no comprehensive estimation of the role of …

A large volume of clinical and experimental evidence documents sex differences in brain
anatomy, chemistry, and function, as well as in stress and drug responses. The chronic mild …

Sex differences in behavioral and neurobiological responses to stress are considered to
modulate the prevalence of some psychiatric disorders, including major depression. In the …

Rationale Interactions among stress, serotonin 1A (5-HT 1A) receptors, and the
hypothalamic–pituitary–adrenocortical (HPA) system have been proposed to influence the …

Women are more susceptible than men to certain stress-related psychiatric disorders, such
as depression. Preclinical studies aim to understand these sex differences by studying male …

Chronic stress is often associated with a dysregulation of the hypothalamic-pituitary-adrenal
(HPA) axis, which can greatly increase risk for a number of stress-related diseases …

Sex differences play an important role in depression, the basis of which is an excessive
stress response. We aimed at revealing the neurobiological sex differences in the same …

Gender is an important factor in the vulnerability to develop psychopathologies. At the
biological level, stress-related pathologies such as depression or post-traumatic stress …

Epidemiological studies demonstrate that affective disorders are at least twice as common in
women as in men, but surprisingly, very few preclinical studies have been conducted on …

The chronic mild stress (CMS) procedure was developed in rodents to target anhedonia, the
core symptom of depressive melancholia. Stress exposure has been shown to induce a …