Clinical and molecular impact of concurrent thyroid autoimmune disease and thyroid cancer: From the bench to bedside

VA dos Santos Valsecchi, FR Betoni, LS Ward… - Reviews in Endocrine …, 2024 - Springer
The recent incorporation of immune checkpoint inhibitors targeting the PD-1 (programmed
cell death receptor 1) and CTLA-4 (cytotoxic T lymphocyte antigen 4) pathways into the …

[HTML][HTML] From biomarkers to therapeutic targets: the promise of PD-L1 in thyroid autoimmunity and cancer

G D'Andréa, S Lassalle, N Guevara, B Mograbi… - Theranostics, 2021 - ncbi.nlm.nih.gov
The programmed cell death-1/programmed cell death ligand-1 (PD-1/PD-L1) immune
checkpoint proteins hold promise as diagnostic, prognostic, and therapeutic targets for …

[HTML][HTML] Thyroid autoimmunity and thyroid cancer–the pathogenic connection: a 2018 update

Y Nagayama - Hormone and Metabolic Research, 2018 - thieme-connect.com
The association between thyroid cancer and thyroid autoimmunity has long been suggested,
but remains to be elucidated for several decades. Here the data on this issue are updated by …

[HTML][HTML] Clinical and pathological implications of concurrent autoimmune thyroid disorders and papillary thyroid cancer

LL Cunha, RC Ferreira, MA Marcello… - Journal of thyroid …, 2011 - ncbi.nlm.nih.gov
Cooccurrences of chronic lymphocytic thyroiditis (CLT) and thyroid cancer (DTC) have been
repeatedly reported. Both CLT and DTC, mainly papillary thyroid carcinoma (PTC), share …

Thyroid cancer and thyroid autoimmune disease: A review of molecular aspects and clinical outcomes

NMD Lopes, HHM Lens, A Armani, PC Marinello… - … -Research and Practice, 2020 - Elsevier
Thyroid cancer (TC) is the most prevalent malignant neoplasm that affects the endocrine
system. Hashimoto's thyroiditis (HT), also known as chronic lymphocytic thyroiditis, is the …

Thyroid autoimmune disorders and cancer

SM Ferrari, P Fallahi, G Elia, F Ragusa, I Ruffilli… - Seminars in cancer …, 2020 - Elsevier
In the last decades, many studies conducted in vitro, and in vivo, have shown that thyroid
autoimmunity and thyroid cancer (TC)(mainly papillary TC) can be concomitant, even if the …

[HTML][HTML] The immune landscape of thyroid cancer in the context of immune checkpoint inhibition

G Varricchi, S Loffredo, G Marone, L Modestino… - International journal of …, 2019 - mdpi.com
Immune cells play critical roles in tumor prevention as well as initiation and progression.
However, immune-resistant cancer cells can evade the immune system and proceed to form …

Thyroid autoimmunity and cancer

F Felicetti, MG Catalano, N Fortunati - Endocrine Immunology, 2017 - karger.com
Cancer and autoimmune diseases are often associated in the same individual. The
functional link between the immune system and cancer development is only partially known …

[HTML][HTML] The continuum of thyroid disorders related to immune checkpoint inhibitors: Still many pending queries

MV Deligiorgi, S Sagredou, L Vakkas, DT Trafalis - Cancers, 2021 - mdpi.com
Simple Summary To capitalize on the revolutionary anticancer efficacy of immune
checkpoint inhibitors (ICPi) in an expanding list of tumors, including hematological …

[HTML][HTML] Immune checkpoint inhibitors-related thyroid dysfunction: epidemiology, clinical presentation, possible pathogenesis, and management

L Zhan, H Feng, H Liu, L Guo, C Chen… - Frontiers in …, 2021 - frontiersin.org
Immune checkpoint inhibitors (ICIs) are a group of drugs employed in the treatment of
various types of malignant tumors and improve the therapeutic effect. ICIs blocks negative co …