HPLC-MS/MS method for the simultaneous quantification of dolutegravir, elvitegravir, rilpivirine, darunavir, ritonavir, raltegravir and raltegravir-β-d-glucuronide in …

Y Zheng, R Aboura, S Boujaafar, G Lui, D Hirt… - … of Pharmaceutical and …, 2020 - Elsevier
Therapeutic drug monitoring (TDM) is essential in the optimization of antiretroviral (ARV)
treatments. In this work, we describe a new method for the simultaneous quantification of six …

Development of a simple and rapid method to determine the unbound fraction of dolutegravir, raltegravir and darunavir in human plasma using ultrafiltration and LC …

Y Zheng, G Lui, S Boujaafar, R Aboura… - … of Pharmaceutical and …, 2021 - Elsevier
Dolutegravir, raltegravir and darunavir are three antiretroviral drugs widely used in
combined antiretroviral therapies. These three drugs are highly bound to plasma proteins …

[PDF][PDF] Development and validation of RP-HPLC method for the estimation of dolutegravir and rilpivirine in bulk and pharmaceutical dosage form and its application to …

B Veeraswami, VMK Naveen - DEVELOPMENT, 2019 - academia.edu
Objective: The present paper describes a simple, accurate, and precise reversed-phase
high-performance liquid chromatography (HPLC) method for rapid and simultaneous …

UPLC–MS/MS method for the simultaneous quantification of three new antiretroviral drugs, dolutegravir, elvitegravir and rilpivirine, and other thirteen antiretroviral …

M Simiele, A Ariaudo, A De Nicolò, F Favata… - … of pharmaceutical and …, 2017 - Elsevier
Abstract Rilpivirine (RPV), dolutegravir (DTG) and elvitegravir (EVG) are the latest
antiretroviral drugs approved for treatment of HIV infection. Currently, poor information is …

[HTML][HTML] A new validated stability-indicating RP-HPLC method for simultaneous quantification of dolutegravir and lamivudine in bulk and pharmaceutical dosage form

K Noorbasha, S Nurbhasha - Future Journal of Pharmaceutical Sciences, 2020 - Springer
Background A fresh selective, rapid, accurate, precise and RP-HPLC stability-indicating
method was developed and validated for the quantitative simultaneous determination of …

[HTML][HTML] Development of an HPLC–UV assay method for the simultaneous quantification of nine antiretroviral agents in the plasma of HIV-infected patients

N Charbe, S Baldelli, V Cozzi, S Castoldi… - Journal of …, 2016 - Elsevier
A new method using high-performance liquid chromatography coupled with ultra violet
detection (HPLC–UV) was developed and validated for the simultaneous quantification of …

A New Stability Indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Dolutegravir and Rilpivirine in Bulk and its Dosage Forms …

Y Ismail, MVV Prasad, SM Shaheedha… - Iranian Journal of …, 2019 - vclass.sbmu.ac.ir
The objective of the work is to develop and validate a new, simple, highly sensitive, stability
indicating RPHPLC method for simultaneous estimation of Dolutegravir and Rilpivirine in …

Development and validation of an UPLC-MS/MS bioanalytical method for simultaneous quantification of the antiretroviral drugs dolutegravir, elvitegravir, raltegravir …

PDJ Bollen, MJA de Graaff-Teulen, S Schalkwijk… - … of chromatography B, 2019 - Elsevier
Dolutegravir, elvitegravir, raltegravir, nevirapine and etravirine are antiretroviral drugs used
as part of combined antiretroviral treatment for HIV-infection. For quantification of these …

Development and validation of an HPLC‐UV method for quantification of elvitegravir and two other new antiretrovirals, dolutegravir and rilpivirine, in the plasma of HIV …

M Tempestilli, A Ammassari, A D'Avolio… - Biomedical …, 2018 - Wiley Online Library
Therapeutic drug monitoring may be crucial in selected clinical conditions for the
management of HIV infection. In recent years, new antiretrovirals have been introduced and …

Development and validation of a chromatographic ultraviolet method for the simultaneous quantification of dolutegravir and rilpivirine in human plasma

V Cozzi, N Charbe, S Baldelli, S Castoldi… - Therapeutic Drug …, 2016 - journals.lww.com
Background: We have developed and validated a high-performance liquid chromatographic
method for the simultaneous quantification, in human plasma, of dolutegravir, a new human …