The ongoing conventional drugs for leishmaniasis treatment are insufficient. The present
study aimed to assess 6-gingerol alone and in combination with amphotericin B on …

Objectives The aim of this study was to investigate and characterize the efficacy of
asiaticoside in an experimental model of visceral leishmaniasis caused by antimony …

Abstract Treatment of leishmaniasis by conventional synthetic compounds has faced a
serious challenge worldwide. This study was performed to evaluate the effect and modes of …

Purpose Cuminaldehyde (CA), an oxidized aldehyde monoterpene, is a major essential oil
component in cumin seeds, which has shown different promising medical effects. In this …

Background: Pentavalent antimonials such as meglumine antimoniate (MA, Glucantime), are
the first-line treatment against leishmaniasis, but at present, they have basically lost their …

Present treatment regimen on visceral leishmaniasis has multiple limitations including
severe side effects, toxicity, and resistance of Leishmania strains. Amphotericin B is a well …

Introduction Leishmaniasis denotes a significant health challenge worldwide with no
ultimate treatment. The current study investigated the biological effects of gamma-terpinene …

Phenolic compounds (PCs) are well-known phytochemicals found in plants that have been
studied for their pharmacological properties. In particular, the potentialities of PCs as anti …

The current medications used to treat leishmaniasis have many side effects for patients; in
addition, some cases of the disease are refractory to treatment. Therefore, the search for …

Leishmaniasis is a widespread tropical infection caused by different species of Leishmania
protozoa. Many of the available drugs against the disease are toxic and in certain cases …