Compassionate use of remdesivir in children with COVID-19

A Méndez-Echevarría, A Pérez-Martínez… - European journal of …, 2021 - Springer
Children represent a minority of total COVID-19 cases, but studies have reported severe
disease and death in pediatric patients. Remdesivir (RDV) has recently demonstrated …

Compassionate use of remdesivir in children with severe COVID-19

DL Goldman, ML Aldrich, SHF Hagmann… - …, 2021 - publications.aap.org
OBJECTIVES: Remdesivir shortens time to recovery in adults with severe coronavirus
disease 2019 (COVID-19), but its efficacy and safety in children are unknown. We describe …

Remdesivir use in pediatric patients for SARS-CoV-2 treatment: single academic center study

AM Samuel, LL Hacker, J Zebracki… - The Pediatric …, 2023 - journals.lww.com
Background: Millions of children in the United States have been infected with severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), with many infections leading to …

[HTML][HTML] Remdesivir: the first FDA-approved anti-COVID-19 Treatment for Young Children

A Chera, A Tanca - Discoveries, 2022 - ncbi.nlm.nih.gov
Following the emergence of the SARS-CoV-2 pandemic, finding efficient forms of treatment
is seen as a priority for both adults and children. On April 25, 2022, remdesivir has become …

Multicenter interim guidance on use of antivirals for children with coronavirus disease 2019/severe acute respiratory syndrome coronavirus 2

K Chiotos, M Hayes, DW Kimberlin… - Journal of the …, 2021 - academic.oup.com
Background Although coronavirus disease 2019 (COVID-19) is a mild infection in most
children, a small proportion develop severe or critical illness. Data describing agents with …

Remdesivir for the treatment of COVID 19: review of the pharmacological properties, safety and clinical effectiveness

A Mechineni, H Kassab, R Manickam - Expert Opinion on Drug …, 2021 - Taylor & Francis
Introduction Remdesivir is a nucleoside analog that inhibits viral RNA replication by blocking
RNA-dependent RNA polymerase. First developed and tested during the Ebola epidemic …

Neonates with SARS-CoV-2 infection and pulmonary disease safely treated with remdesivir

B Saikia, J Tang, S Robinson, S Nichani… - The Pediatric …, 2021 - journals.lww.com
We describe 2 expremature infants presenting with SARS-CoV-2-related pulmonary disease
in their second and fifth week of life needing support with mechanical ventilation. Both …

Remdesivir: a review in COVID-19

HA Blair - Drugs, 2023 - Springer
Remdesivir (Veklury®), a nucleotide analogue prodrug with broad-spectrum antiviral activity,
is approved for the treatment of coronavirus disease 2019 (COVID-19), the illness caused by …

[HTML][HTML] FDA approval of remdesivir—a step in the right direction

D Rubin, K Chan-Tack, J Farley… - New England Journal of …, 2020 - Mass Medical Soc
FDA Approval of Remdesivir On October 22, 2020, on the basis of the results of three phase
3 clinical trials, the FDA approved remdesivir for use in adults and pediatric patients (12 …

Sinus bradycardia in a pediatric patient treated with remdesivir for acute coronavirus disease 2019: a case report and a review of the literature

EJ Chow, B Maust, KM Kazmier… - Journal of the Pediatric …, 2021 - academic.oup.com
Remdesivir is an RNA polymerase inhibitor that is commonly used in the treatment of
patients with severe acute coronavirus disease 2019 (COVID-19). As the severe acute …