Personality change in a trial of psilocybin therapy v. escitalopram treatment for depression

B Weiss, I Ginige, L Shannon, B Giribaldi… - Psychological …, 2024 - cambridge.org
BackgroundPsilocybin Therapy (PT) is being increasingly studied as a psychiatric
intervention. Personality relates to mental health and can be used to probe the nature of PT's …

Effects of psilocybin therapy on personality structure

D Erritzoe, L Roseman, MM Nour… - Acta Psychiatrica …, 2018 - Wiley Online Library
Objective To explore whether psilocybin with psychological support modulates personality
parameters in patients suffering from treatment‐resistant depression (TRD). Method Twenty …

How does psilocybin therapy work? An exploration of experiential avoidance as a putative mechanism of change

RJ Zeifman, AC Wagner, CM Monson… - Journal of Affective …, 2023 - Elsevier
Background Psilocybin therapy is receiving attention as a mental health intervention with
transdiagnostic potential. In line with psychotherapeutic research, qualitative research has …

Trial of psilocybin versus escitalopram for depression

R Carhart-Harris, B Giribaldi, R Watts… - … England Journal of …, 2021 - Mass Medical Soc
Background Psilocybin may have antidepressant properties, but direct comparisons
between psilocybin and established treatments for depression are lacking. Methods In a …

Efficacy and safety of psilocybin-assisted treatment for major depressive disorder: Prospective 12-month follow-up

N Gukasyan, AK Davis, FS Barrett… - Journal of …, 2022 - journals.sagepub.com
Background: Preliminary data suggest that psilocybin-assisted treatment produces
substantial and rapid antidepressant effects in patients with major depressive disorder …

Psilocybin-assisted therapy for major depressive disorder: An exploratory placebo-controlled, fixed-order trial

J Sloshower, PD Skosnik… - Journal of …, 2023 - journals.sagepub.com
Background: Several early phase studies have demonstrated that psilocybin-assisted
therapy has rapid-acting and persisting antidepressant effects from just one or two doses …

[HTML][HTML] Psilocybin with psychological support for treatment-resistant depression: six-month follow-up

RL Carhart-Harris, M Bolstridge, CMJ Day, J Rucker… - …, 2018 - Springer
Rationale Recent clinical trials are reporting marked improvements in mental health
outcomes with psychedelic drug-assisted psychotherapy. Objectives Here, we report on …

[HTML][HTML] Unique psychological mechanisms underlying psilocybin therapy versus escitalopram treatment in the treatment of major depressive disorder

B Weiss, L Roseman, B Giribaldi, DJ Nutt… - International Journal of …, 2024 - Springer
The mechanisms by which Psilocybin Therapy (PT) improves depression remain an
important object of study, with scientists actively exploring acute psychological experiences …

The effects of psilocybin on cognitive and emotional functions in healthy participants: Results from a phase 1, randomised, placebo-controlled trial involving …

JJ Rucker, L Marwood, RLJ Ajantaival… - Journal of …, 2022 - journals.sagepub.com
Background: Psilocybin, a psychoactive serotonin receptor partial agonist, has been
reported to acutely reduce clinical symptoms of depressive disorders. Psilocybin's effects on …

Will psilocybin lose its magic in the clinical setting?

C Hayes, M Wahba, S Watson - Therapeutic advances in …, 2022 - journals.sagepub.com
Psilocybin as a novel treatment for depression is garnering a lot of attention from both the
mainstream media and the academic community. Although phase 3 trials are only just …