[HTML][HTML] Fatty acids and evolving roles of their proteins in neurological, cardiovascular disorders and cancers

R Mallick, S Basak, AK Duttaroy - Progress in lipid research, 2021 - Elsevier
The dysregulation of fat metabolism is involved in various disorders, including
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …

Fatty acid transporting proteins: Roles in brain development, aging, and stroke

W Zhang, R Chen, T Yang, N Xu, J Chen, Y Gao… - … and Essential Fatty …, 2018 - Elsevier
Polyunsaturated fatty acids are required for the brain development and significantly impact
aging and stroke. Due to the hydrophobicity of fatty acids, fatty acids transportation related …

Fatty acid transport proteins, implications in physiology and disease

M Kazantzis, A Stahl - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2012 - Elsevier
Uptake of long-chain fatty acids plays pivotal roles in metabolic homeostasis and human
physiology. Uptake rates must be controlled in an organ-specific fashion to balance storage …

SLC27 fatty acid transport proteins

CM Anderson, A Stahl - Molecular aspects of medicine, 2013 - Elsevier
The uptake and metabolism of long chain fatty acids (LCFA) are critical to many
physiological and cellular processes. Aberrant accumulation or depletion of LCFA underlie …

Fatty acid transport proteins: a current view of a growing family

A Stahl, RE Gimeno, LA Tartaglia, HF Lodish - Trends in Endocrinology & …, 2001 - cell.com
Long-chain fatty acids (LCFAs) are a major caloric component of our diet and are key
metabolites for energy generation and storage. Physiological uptake of LCFAs across cell …

[HTML][HTML] The multiple roles of fatty acid handling proteins in brain

VSF Moullé, C Cansell, S Luquet… - Frontiers in …, 2012 - frontiersin.org
Lipids are essential components of a living organism as energy source but also as
constituent of the membrane lipid bilayer. In addition fatty acid (FA) derivatives interact with …

Fatty acid transport protein expression in human brain and potential role in fatty acid transport across human brain microvessel endothelial cells

RW Mitchell, NH On, MR Del Bigio… - Journal of …, 2011 - Wiley Online Library
J. Neurochem.(2011) 117, 735–746. Abstract The blood‐brain barrier (BBB), formed by the
brain capillary endothelial cells, provides a protective barrier between the systemic blood …

[HTML][HTML] Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease

JFC Glatz, JJFP Luiken, A Bonen - Physiological reviews, 2010 - journals.physiology.org
Long-chain fatty acids and lipids serve a wide variety of functions in mammalian
homeostasis, particularly in the formation and dynamic properties of biological membranes …

[HTML][HTML] Cellular uptake and intracellular trafficking of long chain fatty acids

MJ McArthur, BP Atshaves, A Frolov, WD Foxworth… - Journal of lipid …, 1999 - ASBMB
While aspects of cellular fatty acid uptake have been studied as early as 50 years ago,
recent developments in this rapidly evolving field have yielded new functional insights on …

Molecular mechanism of long-chain fatty acid uptake

JE Schaffer, HF Lodish - Trends in cardiovascular medicine, 1995 - Elsevier
Most eukaryotic cells are capable of taking up long-chain fatty acids (LCFAs) to be used for a
variety of cellular processes. Low levels of cellular uptake may occur by simple diffusion of …