Thioredoxin-interacting protein (TXNIP) as a target for Alzheimer's disease: Flavonoids and phenols
M Zhang, G Hu, N Shao, Y Qin, Q Chen, Y Wang… - …, 2021 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease characterized by amyloid plaques
and tangles that have become the fifth leading cause of death worldwide. Previous studies …
and tangles that have become the fifth leading cause of death worldwide. Previous studies …
Thioredoxin-interacting protein (TXNIP) associated NLRP3 inflammasome activation in human Alzheimer's disease brain
Alzheimer's disease (AD) is the most common form of age-associated dementia
characterized by amyloid-ß plaques and neurofibrillary tangles. Recent studies have …
characterized by amyloid-ß plaques and neurofibrillary tangles. Recent studies have …
Thioredoxin-interacting protein (TXNIP) with focus on brain and neurodegenerative diseases
H Tsubaki, I Tooyama, DG Walker - International journal of molecular …, 2020 - mdpi.com
The development of new therapeutic approaches to diseases relies on the identification of
key molecular targets involved in amplifying disease processes. One such molecule is …
key molecular targets involved in amplifying disease processes. One such molecule is …
Upregulation of thioredoxin-interacting protein in brain of amyloid-β protein precursor/presenilin 1 transgenic mice and amyloid-β treated neuronal cells
Y Wang, Y Wang, V Bharti, H Zhou… - Journal of …, 2019 - content.iospress.com
Oxidative stress has been hypothesized to play a role in the pathophysiology of Alzheimer's
disease (AD). Previously, we found that total nitrosylated protein levels were increased in …
disease (AD). Previously, we found that total nitrosylated protein levels were increased in …
Phytochemicals as potential target on thioredoxin-interacting protein (TXNIP) for the treatment of cardiovascular diseases
P Zhou, Y Ma, X Zhao, F Hua - Inflammopharmacology, 2023 - Springer
Cardiovascular diseases (CVDs) are currently the major cause of death and morbidity on a
global scale. Thioredoxin-interacting protein (TXNIP) is a marker related to metabolism …
global scale. Thioredoxin-interacting protein (TXNIP) is a marker related to metabolism …
Dl-3-n-Butylphthalide Inhibits NLRP3 Inflammasome and Mitigates Alzheimer's-Like Pathology via Nrf2-TXNIP-TrX Axis
CY Wang, Y Xu, X Wang, C Guo, T Wang… - Antioxidants & redox …, 2019 - liebertpub.com
Aims: Oxidative stress and neuroinflammation play important roles in the pathology of
Alzheimer's disease (AD). Thioredoxin-interacting protein (TXNIP), an endogenous inhibitor …
Alzheimer's disease (AD). Thioredoxin-interacting protein (TXNIP), an endogenous inhibitor …
Thioredoxin-interacting protein (TXNIP) in cerebrovascular and neurodegenerative diseases: regulation and implication
Neurological diseases, including acute attacks (eg, ischemic stroke) and chronic
neurodegenerative diseases (eg, Alzheimer's disease), have always been one of the …
neurodegenerative diseases (eg, Alzheimer's disease), have always been one of the …
[HTML][HTML] TXNIP contributes to induction of pro-inflammatory phenotype and caspase-3 activation in astrocytes during Alzheimer's diseases
Neuroinflammation and oxidative stress have been implicated in the pathogenesis of
Alzheimer's disease (AD). Neuroinflammation and oxidative stress are associated with …
Alzheimer's disease (AD). Neuroinflammation and oxidative stress are associated with …
ER stress associated TXNIP-NLRP3 inflammasome activation in hippocampus of human Alzheimer's disease
Although the exact etiology of Alzheimer's disease (AD) is poorly understood, experimental
and clinical evidences suggest the contribution of neuroinflammation in the pathogenesis of …
and clinical evidences suggest the contribution of neuroinflammation in the pathogenesis of …
Quinones as preventive agents in Alzheimer's diseases: focus on NLRP3 inflammasomes
D Chen, H Gao, C Peng, S Pei, A Dai… - Journal of Pharmacy …, 2020 - academic.oup.com
Objectives Alzheimer's disease (AD) is a hidden neurological degenerative disease, which
main clinical manifestations are cognitive dysfunction, memory impairment and mental …
main clinical manifestations are cognitive dysfunction, memory impairment and mental …