[HTML][HTML] Thymoquinone as a potential adjuvant therapy for cancer treatment: evidence from preclinical studies

AGM Mostofa, MK Hossain, D Basak… - Frontiers in …, 2017 - frontiersin.org
Thymoquinone (TQ), the main bioactive component of Nigella sativa, has been found to
exhibit anticancer effects in numerous preclinical studies. Due to its multitargeting nature, TQ …

[HTML][HTML] Therapeutic potential of thymoquinone in combination therapy against cancer and cancer stem cells

Z Fatfat, M Fatfat, H Gali-Muhtasib - World journal of clinical …, 2021 - ncbi.nlm.nih.gov
The long-term success of standard anticancer monotherapeutic strategies has been
hampered by intolerable side effects, resistance to treatment and cancer relapse. These …

Thymoquinone anticancer discovery: possible mechanisms

AH El-Far - Current drug discovery technologies, 2015 - ingentaconnect.com
Medicinal plants are known for their many advantages, including the ability to treat diseases
such as cancer. Nigella sativa and its active constituent thymoquinone (TQ) have long been …

Thymoquinone: fifty years of success in the battle against cancer models

R Schneider-Stock, IH Fakhoury, AM Zaki… - Drug discovery today, 2014 - Elsevier
Highlights•This year marks 50 years since thymoquinone was isolated from black
seed.•Thymoquinone has had a long history of battling cancer in vitro and in …

Therapeutic implications and clinical manifestations of thymoquinone

M Alam, GM Hasan, MM Ansari, R Sharma, DK Yadav… - Phytochemistry, 2022 - Elsevier
Thymoquinone (TQ), a natural phytochemical predominantly found in Nigella sativa, has
been investigated for its numerous health benefits. TQ showed anti-cancer, anti-oxidant, and …

Thymoquinone, an active compound of Nigella sativa: role in prevention and treatment of cancer

SA Almatroodi, A Almatroudi, MA Alsahli… - Current …, 2020 - ingentaconnect.com
Background: Cancer is the leading cause of death worldwide and the current mode of
cancer treatment causes side effects on normal cells and are still the key challenges in its' …

[HTML][HTML] Chemopreventive and anticancer effects of thymoquinone: cellular and molecular targets

R Gomathinayagam, JH Ha, M Jayaraman… - Journal of cancer …, 2020 - ncbi.nlm.nih.gov
Thymoquinone (TQ) is a bioactive component derived from the seeds of Nigella sativa that
are commonly as black cumin. Evidences indicate that the medicinal properties of TQ have …

Review on molecular and therapeutic potential of thymoquinone in cancer

S Banerjee, S Padhye, A Azmi, Z Wang… - Nutrition and …, 2010 - Taylor & Francis
Thymoquinone (TQ) is the predominant bioactive constituent present in black seed oil
(Nigella sativa) and has been tested for its efficacy against cancer. Here, we summarize the …

Therapeutic potential of thymoquinone in glioblastoma treatment: Targeting major gliomagenesis signaling pathways

FA Chowdhury, MK Hossain… - BioMed research …, 2018 - Wiley Online Library
Glioblastoma multiforme (GBM) is one of the most devastating brain tumors with median
survival of one year and presents unique challenges to therapy because of its aggressive …

[HTML][HTML] Thymoquinone, as a novel therapeutic candidate of cancers

B Almajali, HAN Al-Jamal, WRW Taib, I Ismail… - Pharmaceuticals, 2021 - mdpi.com
To date, natural products are widely used as pharmaceutical agents for many human
diseases and cancers. One of the most popular natural products that have been studied for …