[HTML][HTML] Imaging of Cardiac Fibrosis: How Far Have We Moved From Extracellular to Cellular?

T Telli, A Hosseini, S Settelmeier, D Kersting… - Seminars in Nuclear …, 2024 - Elsevier
Cardiovascular disease is the leading cause of morbidity and mortality worldwide.
Myocardial fibrosis plays an important role in adverse outcomes such as heart failure and …

Myocardial fibrosis: emerging target for cardiac molecular imaging and opportunity for image-guided therapy

FM Bengel, J Diekmann, A Hess… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Myocardial fibrosis is a major contributor to the development and progression of heart
failure. Significant progress in the understanding of its pathobiology has led to the …

Myocardial fibrosis: why image, how to image and clinical implications

R Bing, MR Dweck - Heart, 2019 - heart.bmj.com
The current era has seen major advances in myocardial imaging. We are now able to
assess cardiac anatomy, function, tissue composition and disease activity across a wide …

[HTML][HTML] Recent Progresses in the Multimodality Imaging Assessment of Myocardial Fibrosis

H Zhu, K Xie, Y Qian, Z Zou, M Jiang… - Reviews in Cardiovascular …, 2024 - imrpress.com
Myocardial fibrosis, a common pathophysiological consequence of various cardiovascular
diseases, is characterized by fibroblast activation and excessive deposition of extracellular …

[HTML][HTML] Many paths lead to CV outcomes: a potential need for image-guided precision medicine

TC Wong, EB Schelbert - JACC: Cardiovascular Imaging, 2016 - jacc.org
Vulnerability among cardiac patients is multifactorial and may arise from myocardial
interstitial disease (eg, fibrosis or amyloidosis) or other derangements such as valve …

Imaging of Cardiac Fibrosis: An Update, From the AJR Special Series on Imaging of Fibrosis

GR Karur, A Aneja, J Stojanovska… - American Journal of …, 2023 - Am Roentgen Ray Soc
Myocardial fibrosis (MF) is defined as excessive production and deposition of extra-cellular
matrix (ECM) proteins that result in pathologic myocardial remodeling. Three types of MF …

Imaging tools for assessment of myocardial fibrosis in humans: the need for greater detail

S Hassan, CJ Barrett, DJ Crossman - Biophysical reviews, 2020 - Springer
Myocardial fibrosis is recognized as a key pathological process in the development of
cardiac disease and a target for future therapeutics. Despite this recognition, the assessment …

In vitro Assays and Imaging Methods for Drug Discovery for Cardiac Fibrosis

G Palano, A Foinquinos, E Müllers - Frontiers in Physiology, 2021 - frontiersin.org
As a result of stress, injury, or aging, cardiac fibrosis is characterized by excessive
deposition of extracellular matrix (ECM) components resulting in pathological remodeling …

Cardiac Applications of Fibroblast Activation Protein Imaging.

J Diekmann, FM Bengel - PET clinics, 2023 - europepmc.org
Several promising applications of cardiac molecular fibroblast activation protein (FAP)
imaging are emerging. Myocardial fibrosis plays a key role in the complex process of cardiac …

[HTML][HTML] Cardiac Fibrosis in heart failure: Focus on non-invasive diagnosis and emerging therapeutic strategies

S Ravassa, B López, TA Treibel, G San José… - Molecular Aspects of …, 2023 - Elsevier
Heart failure is a leading cause of mortality and hospitalization worldwide. Cardiac fibrosis,
resulting from the excessive deposition of collagen fibers, is a common feature across the …