The interior of the eukaryotic cell nucleus has a crowded and heterogeneous environment
packed with chromatin polymers, regulatory proteins, and RNA molecules. Chromatin …

Nuclear DNA in eukaryotes is wrapped around histone proteins to form nucleosomes on a
chromatin fiber. Dynamic folding of the chromatin fiber into loops and variations in the …

The genetic material of eukaryotes is segregated into transcriptionally active euchromatin
and silent heterochromatin compartments. The spatial arrangement of chromatin …

In eukaryotic cells, protein and RNA factors involved in genome activities like transcription,
RNA processing, DNA replication, and repair accumulate in self-organizing membraneless …

Eukaryotic chromatin is a negatively charged polymer consisting of genomic DNA, histones,
and various nonhistone proteins. Because of its highly charged character, the structure of …

In this issue of Cell, Strickfaden et al. reveal that condensed chromatin shows a solid-like
behavior at mesoscales both in vitro and in living cells. Using fluorescent microscopy …

Chromatin is partitioned on multiple length scales into subcompartments that differ from
each other with respect to their molecular composition and biological function. It is a key …

Cells compartmentalize their genome into active and inactive parts that contain distinct
histone marks and are differently packaged. Recent work has shed new light on the …

Chromatin in eukaryotic cells is a negatively charged long polymer consisting of DNA,
histones, and various associated proteins. With its highly charged and heterogeneous …

Understanding the mechanisms that trigger chromatin compaction, its patterns, and the
factors they depend on, is a fundamental and still open question in Biology. Chromatin …