Nonalcoholic fatty liver disease (NAFLD) is a growing worldwide epidemic and an important
risk factor for the development of insulin resistance, type 2 diabetes, nonalcoholic …

The AMP-activated protein kinase (AMPK) is a highly conserved master regulator of
metabolism, whose activation has been proposed to be therapeutically beneficial for the …

Nonalcoholic fatty liver diseases (NAFLDs), especially nonalcoholic steatohepatitis (NASH),
have become a major cause of liver transplant and liver-associated death. However, the …

Nonalcoholic fatty liver disease is a highly prevalent component of disorders associated with
disrupted energy homeostasis. Although dysregulation of the energy sensor AMP-activated …

AMP-activated protein kinase (AMPK) plays a key role in integrating metabolic pathways in
response to energy demand. We identified a mutation in the γ1 subunit (γ1 D316A) that …

No approved therapies are available for nonalcoholic steatohepatitis (NASH). Adenosine
monophosphate–activated protein kinase (AMPK) is a central regulator of cell metabolism; …

5′ AMP-activated protein kinase (AMPK) is known as metabolic sensor in mammalian cells
that becomes activated by an increasing adenosine monophosphate (AMP)/adenosine …

It is now becoming evident that the liver has an important role in the control of whole body
metabolism of energy nutrients. In this review, we focus on recent findings showing that AMP …

Dysregulation of hepatic lipid and cholesterol metabolism is a significant contributor to
cardiometabolic health, resulting in excessive liver lipid accumulation and ultimately non …

Background AMP kinase (AMPK) is an energy sensor implicated in regulation of lipid
metabolism, inflammation, and insulin sensitivity. We aimed to assess efficacy and safety of …