Ulipristal acetate versus leuprolide acetate for uterine fibroids

J Donnez, J Tomaszewski, F Vázquez… - … England Journal of …, 2012 - Mass Medical Soc
Background The efficacy and side-effect profile of ulipristal acetate as compared with those
of leuprolide acetate for the treatment of symptomatic uterine fibroids before surgery are …

[HTML][HTML] Ulipristal acetate versus placebo for fibroid treatment before surgery

J Donnez, TF Tatarchuk, P Bouchard… - … England Journal of …, 2012 - Mass Medical Soc
Background The efficacy and safety of oral ulipristal acetate for the treatment of symptomatic
uterine fibroids before surgery are uncertain. Methods We randomly assigned women with …

[HTML][HTML] Efficacy and safety of repeated use of ulipristal acetate in uterine fibroids

J Donnez, R Hudecek, O Donnez, D Matule… - Fertility and sterility, 2015 - Elsevier
Objective To investigate the efficacy and safety of repeated 12-week courses of 5 or 10 mg
daily of ulipristal acetate for intermittent treatment of symptomatic uterine fibroids. Design …

Ulipristal acetate: a novel pharmacological approach for the treatment of uterine fibroids

N Biglia, S Carinelli, A Maiorana… - Drug design …, 2014 - Taylor & Francis
Uterine fibroids are the most common benign tumors of the female genital tract. The
management of symptomatic fibroids has traditionally been surgical; however, alternative …

[HTML][HTML] Long-term medical management of uterine fibroids with ulipristal acetate

J Donnez, O Donnez, D Matule, HJ Ahrendt… - Fertility and sterility, 2016 - Elsevier
Objective To investigate the efficacy and safety of repeated 12-week courses of 5 or 10 mg
daily ulipristal acetate for intermittent treatment of symptomatic uterine fibroids. Design …

[HTML][HTML] Long-term treatment of uterine fibroids with ulipristal acetate☆

J Donnez, F Vázquez, J Tomaszewski, K Nouri… - Fertility and sterility, 2014 - Elsevier
Objective To investigate the efficacy and safety of ulipristal acetate (UPA) for long-term
treatment of symptomatic uterine fibroids. Design Repeated intermittent open-label UPA …

[HTML][HTML] First series of 18 pregnancies after ulipristal acetate treatment for uterine fibroids

M Luyckx, JL Squifflet, P Jadoul, R Votino… - Fertility and sterility, 2014 - Elsevier
Objective To study the pregnancy rate after ulipristal acetate (UPA) therapy for fibroids.
Design Retrospective analysis of a series of 52 patients prospectively included in the …

[HTML][HTML] Safety after extended repeated use of ulipristal acetate for uterine fibroids

BCJM Fauser, J Donnez, P Bouchard, DH Barlow… - PLoS …, 2017 - journals.plos.org
Objective To assess long term safety of extended repeated 3-month courses of ulipristal
acetate (UPA) 10 mg/day, for up to 8 courses, with focus on endometrial and laboratory …

Elagolix for heavy menstrual bleeding in women with uterine fibroids

WD Schlaff, RT Ackerman, A Al-Hendy… - … England Journal of …, 2020 - Mass Medical Soc
Background Uterine fibroids are hormone-responsive neoplasms that are associated with
heavy menstrual bleeding. Elagolix, an oral gonadotropin-releasing hormone antagonist …

Treatment of uterine fibroid symptoms with relugolix combination therapy

A Al-Hendy, AS Lukes, AN Poindexter III… - … England Journal of …, 2021 - Mass Medical Soc
Background Uterine fibroids are a common cause of heavy menstrual bleeding and pain.
Treatment with the combination of relugolix (an oral gonadotropin-releasing hormone …