The combination of therapeutic materials and biocompatible scaffolds to create
multifunctional scaffolds with therapeutic and restorative functions has been investigated as …

The treatment of bone defect caused by osteosarcoma remains an intractable problem.
Scaffolds with multi-functions are the potential candidates to kill recurrent tumor and to repair …

Conventional biomaterial-mediated osteosarcoma therapy mainly focuses on its antitumor
effect yet often fails to overcome the problem of post-treatment bone tissue defect repair …

3D Printed biodegradable polymeric scaffolds are critical to repair a bone defect, which can
provide the individual porous and network microenvironments for cell attachment and bone …

For treatment of bone tumor and regeneration of bone defects, the biomaterials should
possess the ability to kill tumor cells and regenerate bone defect simultaneously. To date …

After an osteosarcoma excision, recurrence, large bone defects, and soft tissue injury are
significant challenges for clinicians. Conventional treatment by implanting bone replacement …

After resection of bone tumour, the risk of cancer recurrence and numerous bone defects
continues to threaten the health of patients. To overcome the challenge, we developed a …

Osteosarcoma has the characteristics of rapid recurrence, metastasis, and difficulty in
repairing bone defects caused by tumorectomy. A therapeutic strategy with multimode …

Bone defects caused by tumors are difficult to repair clinically because of their poor
morphology and residual tumor cell-induced recurrence. Scaffolds with the dual function of …

Photothermal therapy (PTT) has been extensively explored as a promising alternative
therapeutic approach for many malignant tumors. However, PTT agents never repair bone …