In this perspective article, we focus on recent developments in the theory of charge effects in
biological DNA-related systems. The electrostatic effects on different levels of DNA …

Many proteins" bind" DNA through positively charged amino acids on their surfaces.
However, to overcome significant energetic and topological obstacles, proteins that bend or …

We investigate the complexation behavior between a semiflexible charged polymer and an
oppositely charged sphere with parameters appropriate for the DNA-histone system. We …

Electrostatic interactions have important effects on the physical properties of
macromolecules. 1, 2 The DNA molecule is a case of special interest where many …

Extensive atomic force and electron microscopy reveal a new, generic DNA-colloid complex
with a fixed number of DNA bases per colloid. The fiber shaped complex is stable in the …

▪ Abstract The genomes of higher cells consist of double-helical DNA, a densely charged
polyelectrolyte of immense length. The intrinsic physical properties of DNA, as well as the …

DNA-DNA interactions are important for genome compaction and transcription regulation. In
studies of such complex processes, DNA is often modeled as a homogeneously charged …

Electrostatic interactions between DNA and DNA-packaging proteins, the histones,
contribute substantially to stability of eukaryotic chromatin on all levels of its organization …

Divalent cations, ie, calcium, magnesium, and others, are able to enhance the ability of DNA
to interact with membranes that are composed of zwitterionic lipids such as …

U:“physiological” conditions (a 0.1 molar solution of NaCl), a DNA molecule takes on the
form of a disordered coil with a radius of gyration of several micrometers; if any lengths of the …