[HTML][HTML] Molecular mechanisms of obesity-induced osteoporosis and muscle atrophy

B Roy, ME Curtis, LS Fears, SN Nahashon… - Frontiers in …, 2016 - frontiersin.org
Obesity and osteoporosis are two alarming health disorders prominent among middle and
old age populations, and the numbers of those affected by these two disorders are …

[HTML][HTML] Cellular and molecular mechanisms associating obesity to bone loss

YS Forte, M Renovato-Martins, C Barja-Fidalgo - Cells, 2023 - mdpi.com
Obesity is an alarming disease that favors the upset of other illnesses and enhances
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …

[HTML][HTML] Obesity, osteoporosis and bone metabolism

K Gkastaris, DG Goulis, M Potoupnis… - … of musculoskeletal & …, 2020 - ncbi.nlm.nih.gov
Obesity and osteoporosis have become major global health problems over the last decades
as their prevalence is increasing. The interaction between obesity and bone metabolism is …

Novel insights into the complex architecture of osteoporosis molecular genetics

FA Saad - Annals of the New York Academy of Sciences, 2020 - Wiley Online Library
Osteoporosis is a prevalent osteodegenerative disease and silent killer linked to a decrease
in bone mass and decline of bone microarchitecture, due to impaired bone matrix …

[HTML][HTML] Obesity and bone health: a complex link

J Hou, C He, W He, M Yang, X Luo, C Li - Frontiers in cell and …, 2020 - frontiersin.org
So far, the connections between obesity and skeleton have been extensively explored, but
the results are inconsistent. Obesity is thought to affect bone health through a variety of …

[HTML][HTML] Osteoporosis and obesity: Role of Wnt pathway in human and murine models

G Colaianni, G Brunetti, MF Faienza… - World journal of …, 2014 - ncbi.nlm.nih.gov
Studies concerning the pathophysiological connection between obesity and osteoporosis
are currently an intriguing area of research. Although the onset of these two diseases can …

Muscle, bone, and fat crosstalk: the biological role of myokines, osteokines, and adipokines

B Kirk, J Feehan, G Lombardi, G Duque - Current osteoporosis reports, 2020 - Springer
Abstract Purpose of Review Skeletal muscle and bone are connected anatomically and
physiologically, and play a crucial role in human locomotion and metabolism. Historically …

The obesity of bone

EA Greco, A Lenzi, S Migliaccio - Therapeutic advances in …, 2015 - journals.sagepub.com
During the last decades, obesity and osteoporosis have become important global health
problems, and the belief that obesity is protective against osteoporosis has recently come …

Adipose, bone and muscle tissues as new endocrine organs: role of reciprocal regulation for osteoporosis and obesity development

S Migliaccio, EA Greco, F Wannenes… - … molecular biology and …, 2014 - degruyter.com
The belief that obesity is protective against osteoporosis has recently been revised. In fact,
the latest epidemiologic and clinical studies show that a high level of fat mass, but also …

[HTML][HTML] Obesity: Friend or foe for osteoporosis

S Sharma, VR Tandon, S Mahajan… - Journal of mid-life …, 2014 - journals.lww.com
Osteoporosis and obesity are worldwide health problems. Interestingly, both are associated
with significant morbidity and mortality. Both the diseases have common linkage as bone …