[HTML][HTML] Exploring the potential role of genus Sophora in the management of osteoporosis: a phytochemical and biological review

SH Aly, AMM Elbadry, M El-Shazly… - Frontiers in Natural …, 2023 - frontiersin.org
Bone metabolism is characterized by an interplay between the deposition of bone matrix
and mineralization and the resorption process. Osteoporosis is a form of systemic metabolic …

[HTML][HTML] Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives

HI Abd-Alla, D Souguir, MO Radwan - Archives of pharmacal research, 2021 - Springer
Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third
largest family of flowering plants. The genus Sophora comprises approximately 52 species …

The pharmacology of the genus Sophora (Fabaceae): An updated review

SH Aly, AM Elissawy, OA Eldahshan, MA Elshanawany… - Phytomedicine, 2019 - Elsevier
Abstract Background The genus Sophora (Fabaceae) represents one of the important
medicinal plant genera regarding its chemical constituents and outstanding …

Effects of alkaloids from Sophora flavescens on osteoblasts infected with Staphylococcus aureus and osteoclasts

X Wang, R Zheng, X Huang, Z Mao… - Phytotherapy …, 2018 - Wiley Online Library
Chronic osteomyelitis is primarily caused by infection with Staphylococcus aureus (S.
aureus). Antibiotics are commonly administered; however, it is a challenge to promote bone …

[PDF][PDF] Comparative effects of flavonoids from fructus sophorae on rat osteoblasts in vitro

Y Yang, Y Tian, Q Zhang, X Li, Y Fu, H Pei… - Records of Natural …, 2020 - acgpubs.org
Fructus Sophorae (FS), the dry mature fruit of Sophora japonica Leguminosae, is a valuable
traditional Chinese medicine resource with flavonoids as the major active ingredients. To …

[HTML][HTML] Osteogenic Activities of Trifolirhizin as a Bioactive Compound for the Differentiation of Osteogenic Cells

HM Yun, MH Cho, H Jeong, SH Kim, YH Jeong… - International Journal of …, 2023 - mdpi.com
Plant extracts are widely used as traditional medicines. Sophora flavescens Aiton-derived
natural compounds exert various beneficial effects, such as anti-inflammatory, anticancer …

[HTML][HTML] Potential anti-osteoporotic effects of herbal extracts on osteoclasts, osteoblasts and chondrocytes in vitro

Y Mukudai, S Kondo, T Koyama, C Li, S Banka… - … and Alternative Medicine, 2014 - Springer
Background Osteoporosis (OP) is one of the most serious diseases in the modern world, and
OP patients frequently suffer from fragility fractures in the hip, spine and wrist, resulting in a …

Beneficial effects of the fructus Sophorae extract on experimentally induced osteoporosis in New Zealand white rabbits

L Chakuleska, L CHAKULESKA, A SHKONDROV… - Acta …, 2022 - hrcak.srce.hr
Sažetak Sophora japonica is a source of several flavonol, flavone and isoflavone glycosides
that are reported to positively affect menopausal symptoms including osteoporotic …

The beneficial effect of Radix Dipsaci total saponins on bone metabolism in vitro and in vivo and the possible mechanisms of action

YB Niu, YH Li, XH Kong, R Zhang, Y Sun, Q Li… - Osteoporosis …, 2012 - Springer
The purpose of this study is to investigate the anti-osteoporotic effects of Radix Dipsaci total
saponins (RTS). We showed that RTS was able to improve bone properties by either an …

Antiosteoporotic Activity of Dioscorea alata L. cv. Phyto through Driving Mesenchymal Stem Cells Differentiation for Bone Formation

KY Peng, LY Horng, HC Sung… - Evidence‐Based …, 2011 - Wiley Online Library
The aim of this study was to evaluate the effect of an ethanol extract of the rhizomes of
Dioscorea alata L. cv. Phyto, Dispo85E, on bone formation and to investigate the …