Death of some cells in the mammalian body is clearly programmed. In the immune system
there are many examples of programmed cell death, during development of lymphocytes as …

The immune system provides good models for cell death, a phenomenon now recognized to
be of fundamental importance in many fields of biology. Cell death is strikingly polymorphic …

The progressive acceptance of active cell death by apoptosis' as a fundamental aspect of
the behaviour of normal cells has had a significant impact on many areas of biology …

Publisher Summary This chapter discusses the mechanisms of programmed cell death
(PCD). In many different examples of PCD, regardless of the cell type involved and …

Apoptosis in T and B lymphocytes is involved in all fundamental processes in the immune
system. It is a mechanism to regulate the course of an immune response and to establish …

T lymphocyte death is essential for proper function of the immune system. During the decline
of an immune response, most of the activated T cells die. Cell death is also responsible for …

Stimulation of resting T cells with anti-CD3-T-cell receptor~, TCR) antibodies or mitogenic
lectins such as phytohaemagglutinin (PHA) generally induces a positive response, such as …

Publisher Summary This chapter focuses on the genetic and molecular mechanisms of T
lymphocyte apoptosis and also deals with the various phases of apoptosis initiation …

▪ Abstract Apoptosis of mature T lymphocytes preserves peripheral homeostasis and
tolerance by countering the profound changes in the number and types of T cells stimulated …

Overview: apoptotic signaling pathways in the immune system Page 1 Overview: apoptotic
signaling pathways in the immune system Douglas R. Green Author’s address Douglas R …