The fungal exopolysaccharide galactosaminogalactan mediates virulence by enhancing resistance to neutrophil extracellular traps
Of the over 250 Aspergillus species, Aspergillus fumigatus accounts for up to 80% of
invasive human infections. A. fumigatus produces galactosaminogalactan (GAG), an …
invasive human infections. A. fumigatus produces galactosaminogalactan (GAG), an …
Aspergillus Galactosaminogalactan Mediates Adherence to Host Constituents and Conceals Hyphal β-Glucan from the Immune System
FN Gravelat, A Beauvais, H Liu, MJ Lee… - PLoS …, 2013 - journals.plos.org
Aspergillus fumigatus is the most common cause of invasive mold disease in humans. The
mechanisms underlying the adherence of this mold to host cells and macromolecules have …
mechanisms underlying the adherence of this mold to host cells and macromolecules have …
A Polysaccharide Virulence Factor from Aspergillus fumigatus Elicits Anti-inflammatory Effects through Induction of Interleukin-1 Receptor Antagonist
The galactosaminogalactan (GAG) is a cell wall component of Aspergillus fumigatus that has
potent anti-inflammatory effects in mice. However, the mechanisms responsible for the anti …
potent anti-inflammatory effects in mice. However, the mechanisms responsible for the anti …
Galactosaminogalactan (GAG) and its multiple roles in Aspergillus pathogenesis
C Speth, G Rambach, C Lass-Flörl, PL Howell… - Virulence, 2019 - Taylor & Francis
Aspergillus spp and particularly the species Aspergillus fumigatus are the causative agents
of invasive aspergillosis, a progressive necrotizing pneumonia that occurs in …
of invasive aspergillosis, a progressive necrotizing pneumonia that occurs in …
Aspergillus fumigatus LaeA-Mediated Phagocytosis Is Associated with a Decreased Hydrophobin Layer
TRT Dagenais, SS Giles, V Aimanianda… - Infection and …, 2010 - Am Soc Microbiol
Aspergillus fumigatus is the causal agent of the life-threatening disease invasive
aspergillosis. A. fumigatus laeA deletants, aberrant in toxin biosynthesis and spore …
aspergillosis. A. fumigatus laeA deletants, aberrant in toxin biosynthesis and spore …
Deacetylation of fungal exopolysaccharide mediates adhesion and biofilm formation
The mold Aspergillus fumigatus causes invasive infection in immunocompromised patients.
Recently, galactosaminogalactan (GAG), an exopolysaccharide composed of galactose and …
Recently, galactosaminogalactan (GAG), an exopolysaccharide composed of galactose and …
Galectin-3 enhances neutrophil motility and extravasation into the airways during Aspergillus fumigatus infection
Aspergillus fumigatus is an opportunistic mold that infects patients who are
immunocompromised or have chronic lung disease, causing significant morbidity and …
immunocompromised or have chronic lung disease, causing significant morbidity and …
Ega3 from the fungal pathogen Aspergillus fumigatus is an endo-α-1, 4-galactosaminidase that disrupts microbial biofilms
NC Bamford, F Le Mauff, AS Subramanian, P Yip… - Journal of Biological …, 2019 - ASBMB
Aspergillus fumigatus is an opportunistic fungal pathogen that causes both chronic and
acute invasive infections. Galactosaminogalactan (GAG) is an integral component of the A …
acute invasive infections. Galactosaminogalactan (GAG) is an integral component of the A …
Recent advances in the understanding of the Aspergillus fumigatus cell wall
MJ Lee, DC Sheppard - Journal of microbiology, 2016 - Springer
Over the past several decades, research on the synthesis and organization of the cell wall
polysaccharides of Aspergillus fumigatus has expanded our knowledge of this important …
polysaccharides of Aspergillus fumigatus has expanded our knowledge of this important …
Galactosaminogalactan, a New Immunosuppressive Polysaccharide of Aspergillus fumigatus
T Fontaine, A Delangle, C Simenel, B Coddeville… - PLoS …, 2011 - journals.plos.org
A new polysaccharide secreted by the human opportunistic fungal pathogen Aspergillus
fumigatus has been characterized. Carbohydrate analysis using specific chemical …
fumigatus has been characterized. Carbohydrate analysis using specific chemical …