Ketone bodies have a negative image because of ketoacidosis, one of the acute and serious
complications in diabetes. The negative image persists despite the fact that ketone bodies …

Ketone bodies have a strong negative image in medicine because of ketoacidosis, a life-
threatening complication in diabetes. However, Fang et al. report that ketone bodies exert …

The kidney is a vital organ that carries out significant metabolic functions in our body. Due to
the complexity of its role, the kidney is also susceptible to many disease conditions, such as …

Ketone bodies have emerged as central mediators of metabolic health, and multiple
beneficial effects of a ketogenic diet, impacting metabolism, neuronal pathologies and, to a …

The discovery of insulin approximately a century ago greatly improved the management of
diabetes, including many of its life-threatening acute complications like ketoacidosis. This …

Ketogenic diets have been widely used for weight loss and are increasingly used in the
management of type 2 diabetes. Despite evidence that ketones have multiple positive effects …

During starvation, fasting, or a diet containing little digestible carbohydrates, the circulating
insulin levels are decreased. This promotes lipolysis, and the breakdown of fat becomes the …

Ketone bodies are metabolic fuels and endogenous signaling molecules with multi-systemic
benefits. β-Hydroxybutyrate, the main circulating one during fasting, calorie restriction, and …

In glucose-deprived conditions, ketone bodies are produced by the liver mitochondria,
through the catabolism of fatty acids, and are used peripherally, as an alternative energy …

Objectives. Recent studies have shown that the slightly elevated circulating levels of ketone
bodies (KBs) played a significant role in the treatment of various diseases. This study is …