Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa

AR de Mello Schier… - CNS & Neurological …, 2014 - ingentaconnect.com
Anxiety and depression are pathologies that affect human beings in many aspects of life,
including social life, productivity and health. Cannabidiol (CBD) is a constituent non …

Cannabidiol: a potential new alternative for the treatment of anxiety, depression, and psychotic disorders

MS García-Gutiérrez, F Navarrete, A Gasparyan… - Biomolecules, 2020 - mdpi.com
The potential therapeutic use of some Cannabis sativa plant compounds has been attracting
great interest, especially for managing neuropsychiatric disorders due to the relative lack of …

Cannabinoid CB1 receptor involvement in the actions of CBD on anxiety and coping behaviors in mice

A Austrich-Olivares, MS García-Gutiérrez, L Illescas… - Pharmaceuticals, 2022 - mdpi.com
The anxiolytic and antidepressant properties of cannabidiol (CBD) have been evaluated in
several studies. However, the molecular mechanisms involved in these actions remain …

Evidences for the anti-panic actions of cannabidiol

VP Soares, AC Campos - Current neuropharmacology, 2017 - ingentaconnect.com
Background: Panic disorder (PD) is a disabling psychiatry condition that affects
approximately 5% of the worldwide population. Currently, long-term selective serotonin …

Antidepressant‐like effects of cannabidiol in mice: possible involvement of 5‐HT1A receptors

TV Zanelati, C Biojone, FA Moreira… - British journal of …, 2010 - Wiley Online Library
Background and purpose: Cannabidiol (CBD) is a non‐psychotomimetic compound from
Cannabis sativa that induces anxiolytic‐and antipsychotic‐like effects in animal models …

[HTML][HTML] Antidepressant-like effect induced by Cannabidiol is dependent on brain serotonin levels

AJ Sales, CC Crestani, FS Guimarães… - Progress in Neuro …, 2018 - Elsevier
Cannabidiol (CBD) is a compound of Cannabis sativa with relevant therapeutic potential in
several neuropsychiatric disorders including depression. CBD treatment has shown …

Cannabidiol: Recent advances and new insights for neuropsychiatric disorders treatment

M Premoli, F Aria, SA Bonini, G Maccarinelli… - Life sciences, 2019 - Elsevier
The pharmacological research on the Cannabis sativa-derived compounds has never
terminated. Among the phytocannabinoids without psychotropic effects, the prevalent one in …

Effects of cannabidiol in males and females in two different rat models of depression

L Shbiro, D Hen-Shoval, N Hazut, K Rapps, S Dar… - Physiology & …, 2019 - Elsevier
The current study explores the therapeutic potential of Cannabidiol (CBD), a compound in
the Cannabis plant, using both sexes of 2 “depressive-like” genetic models, Wistar Kyoto …

Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms

GP Silote, A Sartim, A Sales, A Eskelund… - Journal of chemical …, 2019 - Elsevier
Significant limitations with the currently available antidepressant treatment strategies have
inspired research on finding new and more efficient drugs to treat depression. Cannabidiol …

Prohedonic effect of cannabidiol in a rat model of depression

G Shoval, L Shbiro, L Hershkovitz, N Hazut… - …, 2016 - karger.com
Background: Accumulating evidence suggests that cannabidiol (CBD) may be an effective
and safe anxiolytic agent and potentially also an antidepressant. Aim: The objective of this …